Massaut Jacques, Valles Pola, Ghismonde Arnold, Jacques Claudinette Jn, Louis Liseberth Pierre, Zakir Abdulmutalib, Van den Bergh Rafael, Santiague Lunick, Massenat Rose Berly, Edema Nathalie
Nap Kenbe Hospital Haiti, Médecins Sans Frontières OCB, Université Libre de Bruxelles, Rue Antoine Bréart 90, 1060, Brussels, Belgium.
Medical Department, Médecins Sans Frontières OCB, Rue de l'Arbre Bénit 46, 1050, Brussels, Belgium.
BMC Health Serv Res. 2017 Aug 23;17(1):594. doi: 10.1186/s12913-017-2541-4.
The South African Triage Scale (SATS) was developed to facilitate patient triage in emergency departments (EDs) and is used by Médecins Sans Frontières (MSF) in low-resource environments. The aim was to determine if SATS data, reason for admission, and patient age can be used to develop and validate a model predicting the in-hospital risk of death in emergency surgical centers and to compare the model's discriminative power with that of the four SATS categories alone.
We used data from a cohort hospitalized at the Nap Kenbe Surgical Hospital in Haiti from January 2013 to June 2015. We based our analysis on a multivariate logistic regression of the probability of death. Age cutoff, reason for admission categorized into nine groups according to MSF classifications, and SATS triage category (red, orange, yellow, and green) were used as candidate parameters for the analysis of factors associated with mortality. Stepwise backward elimination was performed for the selection of risk factors with retention of predictors with P < 0.05, and bootstrapping was used for internal validation. The likelihood ratio test was used to compare the combined and restricted models. These models were also applied to data from a cohort of patients from the Kunduz Trauma Center, Afghanistan, to validate mortality prediction in an external trauma patients population.
A total of 7618 consecutive hospitalized patients from the Nap Kenbe Hospital were analyzed. Variables independently associated with in-hospital mortality were age > 45 and < = 65 years (odds ratio, 2.04), age > 65 years (odds ratio, 5.15) and the red (odds ratio, 65.08), orange (odds ratio, 3.5), and non-trauma (odds ratio, 3.15) categories. The combined model had an area under the receiver operating characteristic curve (AUROC) of 0.8723 and an AUROC corrected for optimism of 0.8601. The AUROC of the model run on the external data-set was 0.8340. The likelihood ratio test was highly significant in favor of the combined model for both the original and external data-sets.
SATS category, patient age, and reason for admission can be used to predict in-hospital mortality. This predictive model had good discriminative ability to identify ED patients at a high risk of death and performed better than the SATS alone.
南非分诊量表(SATS)旨在促进急诊科患者的分诊,无国界医生组织(MSF)在资源匮乏的环境中使用该量表。目的是确定SATS数据、入院原因和患者年龄是否可用于开发和验证预测急诊外科中心院内死亡风险的模型,并将该模型的辨别力与单独的四个SATS类别进行比较。
我们使用了2013年1月至2015年6月在海地纳普肯贝外科医院住院的队列数据。我们的分析基于死亡概率的多变量逻辑回归。年龄临界值、根据无国界医生组织分类分为九组的入院原因以及SATS分诊类别(红色、橙色、黄色和绿色)被用作分析与死亡率相关因素的候选参数。进行逐步向后消除以选择风险因素,保留P<0.05的预测因子,并使用自举法进行内部验证。似然比检验用于比较组合模型和受限模型。这些模型还应用于来自阿富汗昆都士创伤中心的患者队列数据,以验证外部创伤患者群体中的死亡率预测。
共分析了纳普肯贝医院7618例连续住院患者。与院内死亡率独立相关的变量为年龄>45岁且<=65岁(比值比,2.04)、年龄>65岁(比值比,5.15)以及红色(比值比,65.08)、橙色(比值比,3.5)和非创伤(比值比,3.15)类别。组合模型的受试者工作特征曲线下面积(AUROC)为0.8723,校正乐观度后的AUROC为0.8601。在外部数据集上运行的模型的AUROC为0.8340。似然比检验对于原始数据集和外部数据集均非常显著地支持组合模型。
SATS类别、患者年龄和入院原因可用于预测院内死亡率。该预测模型具有良好的辨别能力,能够识别死亡风险高的急诊科患者,并且比单独使用SATS表现更好。