• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

用于专用分子乳腺断层合成的低剖面碘化钠(铊)γ相机的设计与特性分析

Design and characterization of a low profile NaI(Tl) gamma camera for dedicated molecular breast tomosynthesis.

作者信息

Polemi Andrew M, Niestroy Justin, Stolin Alexander, Jaliparthi Gangadhar, Wojcik Randy, Majewski Stan, Williams Mark B

机构信息

Dept. of Biomedical Engineering, University of Virginia, 415 Lane Road, Charlottesville, VA USA 22908.

Dept. of Physics, University of Virginia, 382 McCormick Rd., Charlottesville, VA USA 22908.

出版信息

Proc SPIE Int Soc Opt Eng. 2016 Aug 28;9969. doi: 10.1117/12.2246561. Epub 2016 Oct 3.

DOI:10.1117/12.2246561
PMID:28835730
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5565202/
Abstract

A new low profile gamma camera is being developed for use in a dual modality (x-ray transmission and gamma-ray emission) tomosynthesis system. Compared to the system's current gamma camera, the new camera has a larger field of view (20×25 cm) to better match the system's x-ray detector (23×29 cm), and is thinner (7.3 cm instead of 10.3 cm) permitting easier camera positioning near the top surface of the breast. It contains a pixelated NaI(Tl) array with a crystal pitch of 2.2 mm, which is optically coupled to a 4×5 array of Hamamatsu H8500C position sensitive photomultiplier tubes (PSPMTs). The manufacturer-provided connector board of each PSPMT was replaced with a custom designed board that a) reduces the 64 channel readout of the 8×8 electrode anode of the H8500C to 16 channels (8X and 8Y), b) performs gain non-uniformity correction, and c) reduces the height of the PSPMT-base assembly, 37.7 mm to 27.87 mm. The X and Y outputs of each module are connected in a lattice framework, and at two edges of this lattice, the X and Y outputs (32Y by 40X) are coupled to an amplifier/output board whose signals are fed via shielded ribbon cables to external ADCs. The camera uses parallel hole collimation. We describe the measured camera imaging performance, including intrinsic and extrinsic spatial resolution, detection sensitivity, uniformity of response, energy resolution for 140 keV gamma rays, and geometric linearity.

摘要

一种新型的低剖面伽马相机正在被开发用于双模态(X射线透射和伽马射线发射)断层合成系统。与该系统当前的伽马相机相比,新相机具有更大的视野(约20×25厘米),以便更好地匹配系统的X射线探测器(约23×29厘米),并且更薄(7.3厘米而非10.3厘米),从而允许在乳房顶表面附近更轻松地定位相机。它包含一个像素化的碘化钠(铊)阵列,晶体间距为2.2毫米,该阵列与滨松H8500C位置灵敏光电倍增管(PSPMT)的4×5阵列进行光学耦合。每个PSPMT制造商提供的连接板被一个定制设计的板所取代,该板a)将H8500C的8×8电极阳极的64通道读出减少到16通道(8X和8Y),b)进行增益不均匀性校正,c)将PSPMT底座组件的高度从37.7毫米降低到27.87毫米。每个模块的X和Y输出以晶格框架连接,在该晶格的两条边上,X和Y输出(32Y×40X)耦合到一个放大器/输出板,其信号通过屏蔽带状电缆馈送到外部ADC。相机使用平行孔准直。我们描述了测量的相机成像性能,包括固有和外在空间分辨率、探测灵敏度、响应均匀性、140keV伽马射线的能量分辨率以及几何线性度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89a/5565202/78787a0ce12a/nihms876165f9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89a/5565202/752b5a28f443/nihms876165f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89a/5565202/3957b9e8e9aa/nihms876165f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89a/5565202/c0789082f841/nihms876165f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89a/5565202/eb607660c6a6/nihms876165f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89a/5565202/a09889f7e374/nihms876165f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89a/5565202/821e11234db7/nihms876165f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89a/5565202/6734102e72d1/nihms876165f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89a/5565202/e7d0d8a74363/nihms876165f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89a/5565202/78787a0ce12a/nihms876165f9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89a/5565202/752b5a28f443/nihms876165f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89a/5565202/3957b9e8e9aa/nihms876165f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89a/5565202/c0789082f841/nihms876165f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89a/5565202/eb607660c6a6/nihms876165f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89a/5565202/a09889f7e374/nihms876165f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89a/5565202/821e11234db7/nihms876165f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89a/5565202/6734102e72d1/nihms876165f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89a/5565202/e7d0d8a74363/nihms876165f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e89a/5565202/78787a0ce12a/nihms876165f9.jpg

相似文献

1
Design and characterization of a low profile NaI(Tl) gamma camera for dedicated molecular breast tomosynthesis.用于专用分子乳腺断层合成的低剖面碘化钠(铊)γ相机的设计与特性分析
Proc SPIE Int Soc Opt Eng. 2016 Aug 28;9969. doi: 10.1117/12.2246561. Epub 2016 Oct 3.
2
Performance of a PSPMT based detector for scintimammography.基于多阳极微通道板光电倍增管的乳腺闪烁成像探测器性能研究
Phys Med Biol. 2000 Mar;45(3):781-800. doi: 10.1088/0031-9155/45/3/315.
3
Development of a pixelated GSO gamma camera system with tungsten parallel hole collimator for single photon imaging.发展具有钨平行孔准直器的像素化 GSO 伽马相机系统,用于单光子成像。
Med Phys. 2012 Feb;39(2):581-8. doi: 10.1118/1.3673774.
4
Performance characteristics of a new pixelated portable gamma camera.新型像素化便携式伽马相机的性能特征。
Med Phys. 2012 Jun;39(6):3435-44. doi: 10.1118/1.4718874.
5
Development of a miniature scintillation camera using an NaI(Tl) scintillator and PSPMT for scintimammography.使用碘化钠(铊)闪烁体和位置灵敏光电倍增管开发用于乳腺闪烁成像的微型闪烁相机。
Phys Med Biol. 2000 Nov;45(11):3481-8. doi: 10.1088/0031-9155/45/11/326.
6
New devices for imaging in nuclear medicine.核医学成像的新设备。
Cancer Biother Radiopharm. 2004 Feb;19(1):121-8. doi: 10.1089/108497804773391766.
7
Development of a dual modality imaging system: a combined gamma camera and optical imager.双模态成像系统的开发:伽马相机与光学成像仪的组合
Phys Med Biol. 2009 Jul 21;54(14):4547-59. doi: 10.1088/0031-9155/54/14/011. Epub 2009 Jun 26.
8
Development of GATE Monte Carlo simulation for a CsI pixelated gamma camera dedicated to high resolution animal SPECT.用于高分辨率动物单光子发射计算机断层扫描的碘化铯像素化伽马相机的GATE蒙特卡罗模拟开发。
Australas Phys Eng Sci Med. 2018 Mar;41(1):31-39. doi: 10.1007/s13246-017-0607-6. Epub 2017 Dec 11.
9
Single tube gamma camera for scintimammography.用于乳腺闪烁造影的单管γ相机。
Anticancer Res. 1997 May-Jun;17(3B):1651-4.
10
An edge-readout, multilayer detector for positron emission tomography.一种正电子发射断层成像的边沿读出式多层探测器。
Med Phys. 2018 Jun;45(6):2425-2438. doi: 10.1002/mp.12906. Epub 2018 May 6.

本文引用的文献

1
Performance characteristics of dedicated molecular breast imaging systems at low doses.低剂量下专用分子乳腺成像系统的性能特征
Med Phys. 2016 Jun;43(6):3062-3070. doi: 10.1118/1.4950873.
2
Comparison of breast specific gamma imaging and molecular breast tomosynthesis in breast cancer detection: Evaluation in phantoms.乳腺癌检测中乳腺特异性γ成像与分子乳腺断层合成的比较:体模评估
Med Phys. 2015 Jul;42(7):4250-9. doi: 10.1118/1.4922398.
3
Breast cancer imaging devices.乳腺癌成像设备。
Semin Nucl Med. 2011 May;41(3):229-41. doi: 10.1053/j.semnuclmed.2010.12.005.
4
Performance evaluation of a hand-held, semiconductor (CdZnTe)-based gamma camera.基于半导体(碲锌镉)的手持式伽马相机的性能评估。
Eur J Nucl Med Mol Imaging. 2003 Jun;30(6):805-11. doi: 10.1007/s00259-002-1067-z. Epub 2003 Apr 3.
5
Performance of a PSPMT based detector for scintimammography.基于多阳极微通道板光电倍增管的乳腺闪烁成像探测器性能研究
Phys Med Biol. 2000 Mar;45(3):781-800. doi: 10.1088/0031-9155/45/3/315.