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1
Dabigatran vs. warfarin in relation to the presence of left ventricular hypertrophy in patients with atrial fibrillation- the Randomized Evaluation of Long-term anticoagulation therapY (RE-LY) study.达比加群酯与华法林在伴有左心室肥厚的房颤患者中的比较——随机长期抗凝治疗评估(RE-LY)研究。
Europace. 2018 Feb 1;20(2):253-262. doi: 10.1093/europace/eux022.
2
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Heart. 2017 May;103(9):672-678. doi: 10.1136/heartjnl-2016-309672. Epub 2016 Oct 28.
3
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS.2016年欧洲心脏病学会(ESC)与欧洲心胸外科学会(EACTS)合作制定的心房颤动管理指南。
Eur Heart J. 2016 Oct 7;37(38):2893-2962. doi: 10.1093/eurheartj/ehw210. Epub 2016 Aug 27.
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Effectiveness and Safety of Dabigatran, Rivaroxaban, and Apixaban Versus Warfarin in Nonvalvular Atrial Fibrillation.达比加群、利伐沙班和阿哌沙班与华法林相比治疗非瓣膜性心房颤动的有效性和安全性。
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5
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Comparative effectiveness and safety of non-vitamin K antagonist oral anticoagulants and warfarin in patients with atrial fibrillation: propensity weighted nationwide cohort study.非维生素K拮抗剂口服抗凝药与华法林在房颤患者中的疗效和安全性比较:倾向评分加权的全国队列研究
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Circ J. 2016;80(3):753-74. doi: 10.1253/circj.CJ-66-0122. Epub 2016 Feb 3.
10
Right Ventricular and Right Atrial Involvement Can Predict Atrial Fibrillation in Patients with Hypertrophic Cardiomyopathy?肥厚型心肌病患者右心室和右心房受累能否预测心房颤动?
Int J Med Sci. 2016 Jan 1;13(1):1-7. doi: 10.7150/ijms.13530. eCollection 2016.

肥厚型心肌病中的心房颤动与抗凝治疗

Atrial Fibrillation and Anticoagulation in Hypertrophic Cardiomyopathy.

作者信息

Camm C Fielder, Camm A John

机构信息

University of Oxford, Oxford.

St George's, University of London.

出版信息

Arrhythm Electrophysiol Rev. 2017 Jun;6(2):63-68. doi: 10.15420/aer.2017.4.2.

DOI:10.15420/aer.2017.4.2
PMID:28835837
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5522714/
Abstract

Hypertrophic cardiomyopathy (HCM) represents a common inherited cardiac disorder with well-known complications Including stroke and sudden cardiac death. There is a recognised association between HCM and the development of AF. This review describes the epidemiology of AF within the HCM population and analyses the risk factors for the development of AF. It further discusses the outcomes associated with AF in this population, including the evidence in support of higher stroke risk in patients with HCM with AF compared with the general AF population. Finally, the evidence and recommendations for anticoagulation in this patient group are addressed.

摘要

肥厚型心肌病(HCM)是一种常见的遗传性心脏疾病,具有包括中风和心源性猝死在内的众所周知的并发症。HCM与房颤的发生之间存在公认的关联。本综述描述了HCM人群中房颤的流行病学,并分析了房颤发生的危险因素。它进一步讨论了该人群中与房颤相关的结局,包括支持HCM合并房颤患者比一般房颤人群有更高中风风险的证据。最后,阐述了该患者群体抗凝治疗的证据和建议。