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A long journey to reproducible results.

作者信息

Lithgow Gordon J, Driscoll Monica, Phillips Patrick

机构信息

Buck Institute for Research on Aging in Novato, California, USA.

Rutgers University in Piscataway, New Jersey, USA.

出版信息

Nature. 2017 Aug 22;548(7668):387-388. doi: 10.1038/548387a.

DOI:10.1038/548387a
PMID:28836615
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5762131/
Abstract
摘要

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本文引用的文献

1
Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects.遗传背景和实验可重复性对鉴定具有稳健长寿效应的化学化合物的影响。
Nat Commun. 2017 Feb 21;8:14256. doi: 10.1038/ncomms14256.
2
Developing a set of guidelines for your research field: a practical approach.为你的研究领域制定一套指南：一种实用方法。
Mol Biol Cell. 2016 Mar 1;27(5):733-8. doi: 10.1091/mbc.E15-09-0618.
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Sorting out the FACS: a devil in the details.梳理荧光激活细胞分选术：细节决定成败。
Cell Rep. 2014 Mar 13;6(5):779-81. doi: 10.1016/j.celrep.2014.02.021.
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Molecular hyperdiversity and evolution in very large populations.非常大的种群中的分子超多样性和进化。
Mol Ecol. 2013 Apr;22(8):2074-95. doi: 10.1111/mec.12281. Epub 2013 Mar 18.
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Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila.Sir2 过表达对秀丽隐杆线虫和果蝇寿命没有影响。
Nature. 2011 Sep 21;477(7365):482-5. doi: 10.1038/nature10296.
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Factors affecting reproducibility between genome-scale siRNA-based screens.影响基于全基因组规模小干扰RNA筛选的重复性的因素。
J Biomol Screen. 2010 Aug;15(7):735-47. doi: 10.1177/1087057110374994. Epub 2010 Jul 12.
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Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.在生命后期喂食雷帕霉素可延长基因异质小鼠的寿命。
Nature. 2009 Jul 16;460(7253):392-5. doi: 10.1038/nature08221. Epub 2009 Jul 8.
8
Antidepressants of the serotonin-antagonist type increase body fat and decrease lifespan of adult Caenorhabditis elegans.血清素拮抗剂类型的抗抑郁药会增加成年秀丽隐杆线虫的体脂并缩短其寿命。
PLoS One. 2008;3(12):e4062. doi: 10.1371/journal.pone.0004062. Epub 2008 Dec 29.
9
An antidepressant that extends lifespan in adult Caenorhabditis elegans.一种可延长成年秀丽隐杆线虫寿命的抗抑郁药。
Nature. 2007 Nov 22;450(7169):553-6. doi: 10.1038/nature05991.
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Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans.白藜芦醇对黑腹果蝇和秀丽隐杆线虫寿命的影响。
Mech Ageing Dev. 2007 Oct;128(10):546-52. doi: 10.1016/j.mad.2007.07.007. Epub 2007 Aug 14.