Liu Chenxi, Zhang Xinping, Liu Chaojie, Ewen Margaret, Zhang Zinan, Liu Guoqin
School of Medicine and Health Management, Tongji Medical School, Huazhong University of Science and Technology, No.13 Hangkong Rd, Wuhan, Hubei Province, China.
China Health Program, La Trobe University, Plenty Road & Kingsbury Drive, Melbourne, VIC, 3086, Australia.
BMC Health Serv Res. 2017 Aug 24;17(1):597. doi: 10.1186/s12913-017-2553-0.
Poor access to affordable insulin results in serious and needless complications and premature deaths for those with diabetes who need this essential medicine. To help address this issue, we assessed insulin availability, prices, affordability and price components in Hubei Province as China has the heaviest burden of diabetes globally.
In 2016, insulin availability and price data was collected in the capital and five other cities. A total of 30 public sector outlets (hospitals and primary care institutions) and 30 private pharmacies were sampled, using an adaptation of the World Health Organization/Health Action International methodology, Data was collected for all human and analogue insulins in stock, then analyzed by type (prandial, basal or pre-mixed) and duration of action. Prices were expressed as Median Price Ratios (MPRs) to Australian PBS prices. Price components were tracked for five insulin products in two cities.. Affordability was assessed as the number of days' wages of the lowest paid unskilled government worker needed to purchase 10 ml 100 IU/ml (approximately 30 days' supply).
Mean availability was highest in public hospitals for prandial (70%), basal (80%) and pre-mixed insulin (90%). In primary care institutions and private pharmacies mean availability ranged from 10% to 33%. Median prices of all insulin types were higher that Australian PBS prices in all three sectors for human and analogue insulins (ranging from1.36-2.59 times). Patients have to pay 4 to 16 days' wages to purchase a month's treatment depending on the insulin type and sector. The largest component of the patient price was the manufacturers' selling price (60%). Taxes in the form of import duties and VAT are applied in some sectors.
The availability of insulin in primary care institutions and private retail pharmacies was very low in Hubei. Only public hospitals had good insulin availability. Insulin prices were high in all sectors making this life-saving medicine unaffordable, especially for those on low incomes. Governments should consider using its bargaining power to reduce prices, abolish taxes on essential medicines such as insulin, and develop strategies for more equitable access to insulin.
对于需要这种必需药物的糖尿病患者而言,难以获得价格可承受的胰岛素会导致严重且不必要的并发症以及过早死亡。为了帮助解决这一问题,鉴于中国是全球糖尿病负担最重的国家,我们评估了湖北省胰岛素的可及性、价格、可承受性及价格构成。
2016年,收集了湖北省省会及其他五个城市的胰岛素可及性和价格数据。采用世界卫生组织/国际卫生行动组织的方法,共抽取了30家公共部门机构(医院和基层医疗机构)和30家私人药店作为样本。收集了所有库存的人胰岛素和类似物胰岛素的数据,然后按类型(餐时、基础或预混)和作用持续时间进行分析。价格以相对于澳大利亚药品福利计划(PBS)价格的中位数价格比(MPR)表示。追踪了两个城市中五种胰岛素产品的价格构成。可承受性通过购买10毫升100国际单位/毫升胰岛素(约30天供应量)所需的最低工资非技术政府工作人员的天数来评估。
餐时胰岛素(70%)、基础胰岛素(80%)和预混胰岛素(90%)在公立医院的平均可及性最高。在基层医疗机构和私人药店,平均可及性在10%至33%之间。在所有三个部门中,所有人胰岛素和类似物胰岛素的各类胰岛素中位数价格均高于澳大利亚PBS价格(范围为1.36至2.59倍)。根据胰岛素类型和部门不同,患者购买一个月的治疗药物需支付4至16天的工资。患者价格的最大组成部分是制造商的售价(60%)。在某些部门,以进口关税和增值税形式征收税费。
湖北省基层医疗机构和私人零售药店的胰岛素可及性非常低。只有公立医院有良好的胰岛素可及性。所有部门的胰岛素价格都很高,使这种救命药物难以承受,尤其是对低收入者而言。政府应考虑利用其议价能力降低价格,取消对胰岛素等基本药物的税费,并制定战略以实现更公平的胰岛素可及性。