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JBRA Assist Reprod. 2014 Dec 27;18(4):127-135. doi: 10.5935/1518-0557.20140018.
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Assisted reproductive technology in Europe, 2013: results generated from European registers by ESHRE.欧洲 2013 年辅助生殖技术:ESHRE 欧洲注册中心获得的结果。
Hum Reprod. 2017 Oct 1;32(10):1957-1973. doi: 10.1093/humrep/dex264.
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Transfer of more than two embryos, regardless of the age of the female partner, is not beneficial for neither the mothers nor the babies: lessons from the Latin American Registry of Assisted Reproductive Techniques.移植超过两个胚胎,无论女性伴侣年龄多大,对母亲和婴儿都没有益处:来自拉丁美洲辅助生殖技术登记处的经验教训。
JBRA Assist Reprod. 2017 Feb 1;21(1):19-22. doi: 10.5935/1518-0557.20170006.
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Assisted reproductive techniques in Latin America: The Latin American Registry, 2013.拉丁美洲的辅助生殖技术:2013年拉丁美洲登记处
JBRA Assist Reprod. 2016 May 1;20(2):49-58. doi: 10.5935/1518-0557.20160013.
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International Committee for Monitoring Assisted Reproductive Technologies world report: Assisted Reproductive Technology 2008, 2009 and 2010.国际辅助生殖技术监测委员会世界报告:2008年、2009年及2010年辅助生殖技术情况
Hum Reprod. 2016 Jul;31(7):1588-609. doi: 10.1093/humrep/dew082. Epub 2016 May 20.
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Assisted reproductive techniques in Latin America: the Latin American Registry, 2013.拉丁美洲的辅助生殖技术:2013年拉丁美洲登记处
Reprod Biomed Online. 2016 Jun;32(6):614-25. doi: 10.1016/j.rbmo.2016.02.012. Epub 2016 Mar 8.
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The International Committee for Monitoring Assisted Reproductive Technology (ICMART) and the World Health Organization (WHO) Revised Glossary on ART Terminology, 2009.国际辅助生殖技术监测委员会(ICMART)和世界卫生组织(WHO)2009 年修订的《ART 术语词汇》。
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Perinatal outcome of singletons and twins after assisted conception: a systematic review of controlled studies.辅助生殖后单胎和双胎的围产期结局:对照研究的系统评价
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拉丁美洲的辅助生殖技术:2014年拉丁美洲登记处

Assisted reproductive techniques in Latin America: The Latin American Registry, 2014.

作者信息

Zegers-Hochschild Fernando, Schwarze Juan Enrique, Crosby Javier A, Musri Carolina, Urbina Maria Teresa

机构信息

Reproductive Medicine Unit - Las Condes Clinic, Chile.

Ethics and Public Policies Program in Human Reproduction, University Diego Portales, Chile.

出版信息

JBRA Assist Reprod. 2017 Sep 1;21(3):164-175. doi: 10.5935/1518-0557.20170034.

DOI:10.5935/1518-0557.20170034
PMID:28837023
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5574636/
Abstract

Multinational data on assisted reproduction techniques undertaken in 2014 were collected from 159 institutions in 15 countries in Latin America. Treatments included IVF/ ICSI, FET, OD, PGD and fertility preservation (FP). 41.34% of IVF/ICSI cycles were performed in women aged 35 to 39 years and 23.35% in women aged 40 and older. After removing cases with total freezing, delivery rate per oocyte retrieval was 25.05% for ICSI and 27.41% for IVF. Multiple births included 20.78% twins and 0.92 % triplets and over. In OD, twins reached 28.93% and triplets 1.07 %. Preterm deliveries reached 16.4% in singletons, 55.02% in twins and 76% in triplets. Perinatal mortality in 18,162 births was 23 per 1000 in singletons, 35 per 1000 in twins, and 36 per 1000 in high-order multiples. Elective single embryo transfer (eSET) represented only 2.63 % of fresh transfers, with a delivery rate of 32.15% per transfer. Elective double embryo transfer (eDET) represented 23.74% of transfers, with a delivery rate of 41.03% per transfer. Among babies born during this period 11,373 (62.6%) were singletons; 6,398 (35.2%) twins, and 391 (2.2%), triplets and more. Given the effect of multiple births on prematurity, morbidity and perinatal mortality, reinforcing the existing trend of reducing the number of embryos transferred is mandatory.

摘要

2014年拉丁美洲15个国家159家机构收集了辅助生殖技术的跨国数据。治疗方法包括体外受精/卵胞浆内单精子注射(IVF/ICSI)、冻融胚胎移植(FET)、卵巢刺激(OD)、植入前基因诊断(PGD)和生育力保存(FP)。41.34%的IVF/ICSI周期是在35至39岁的女性中进行的,23.35%是在40岁及以上的女性中进行的。去除全部冷冻的病例后,ICSI每取卵周期的分娩率为25.05%,IVF为27.41%。多胎妊娠包括20.78%的双胞胎和0.92%的三胞胎及以上。在卵巢刺激中,双胞胎率达28.93%,三胞胎率为1.07%。单胎早产率达16.4%,双胞胎为55.02%,三胞胎为76%。18162例分娩中的围产期死亡率,单胎为每1000例23例,双胞胎为每1000例35例,高阶多胎为每1000例36例。选择性单胚胎移植(eSET)仅占新鲜移植的2.63%,每次移植的分娩率为32.15%。选择性双胚胎移植(eDET)占移植的23.74%,每次移植的分娩率为41.03%。在此期间出生的婴儿中,11373例(62.6%)为单胎;6398例(35.2%)为双胞胎,391例(2.2%)为三胞胎及以上。鉴于多胎妊娠对早产、发病率和围产期死亡率的影响,强化现有减少移植胚胎数量的趋势是必要的。