Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, 33 Russell Street, Toronto, ON M5S 2S1, Canada; Institute of Medical Science, University of Toronto, Faculty of Medicine, Medical Sciences Building, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.
Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, 33 Russell Street, Toronto, ON M5S 2S1, Canada; Institute of Clinical Psychology and Psychotherapy & Center of Clinical Epidemiology and Longitudinal Studies, Technische Universität Dresden, Chemnitzer Str. 46., 01187 Dresden, Germany.
Reprod Toxicol. 2017 Oct;73:214-221. doi: 10.1016/j.reprotox.2017.08.004. Epub 2017 Aug 31.
The objective was to obtain the first ever estimates of the prevalence of binge drinking (defined as four or more standard drinks per occasion) during pregnancy among the general population by country and World Health Organization region. A comprehensive systematic literature search was conducted, followed by country-specific random-effects meta-analyses for those countries with two or more empirical studies. For the remaining countries, the prevalence was predicted via a multilevel fractional response regression model, using country-specific indicators. Regional averages were then estimated. Lastly, the proportion of pregnant women who binge drank during pregnancy out of all women who used any amount of alcohol during pregnancy was estimated for each country. The African Region was estimated to have the highest prevalence of binge drinking during pregnancy, while the Western Pacific Region had the lowest estimated prevalence. The findings indicate that a large portion of pregnancies that are alcohol exposed are being exposed to the most detrimental pattern of drinking - binge drinking.
目的是通过国家和世界卫生组织区域，首次获得一般人群中怀孕期间暴饮（定义为每次饮用四个或更多标准饮品）的流行率估计值。进行了全面的系统文献检索，然后对有两个或更多经验研究的国家进行了特定国家的随机效应荟萃分析。对于其余国家，使用特定国家的指标，通过多级分数响应回归模型预测流行率。然后估计区域平均值。最后，根据每个国家的所有怀孕期间饮酒的女性数量，估算出怀孕期间暴饮的孕妇比例。估计非洲区域怀孕期间暴饮的流行率最高，而西太平洋区域估计的流行率最低。研究结果表明，大量暴露于酒精的妊娠中，有很大一部分是暴露于最有害的饮酒模式 - 暴饮。
