Marks Daniel J B, Smith Philip J, Rahman Farooq Z, Miller Robert F, Ledermann Jonathan A, Bloom Stuart L
Department of Medicine, University College London, London, UK.
Department of Gastroenterology, University College London Hospital, London, UK.
Frontline Gastroenterol. 2011 Jan;2(1):57-62. doi: 10.1136/fg.2010.001990. Epub 2010 Sep 28.
Colitis secondary to cytomegalovirus infection is well recognised and usually straightforward to diagnose. Here two cases are reported in whom all initial investigations failed to demonstrate the presence of virus, with potential adverse consequences for its treatment. A case is made for empirical antiviral therapy despite negative investigations if clinical suspicion is high.
巨细胞病毒感染继发的结肠炎已得到充分认识,通常诊断并不困难。本文报告两例患者,其所有初始检查均未能证实病毒的存在,这可能对其治疗产生不良后果。如果临床怀疑度高,即使检查结果为阴性,也应进行经验性抗病毒治疗。