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Tyr-MIF-1 acts as an opiate antagonist in the tail-flick test.
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Differential activity of the endogenous antiopiate Tyr-MIF-1 after various intensities of stress.
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A Tyr-W-MIF-1 analog containing D-Pro2 discriminates among antinociception in mice mediated by different classes of mu-opioid receptors.
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MIF-1 and Tyr-MIF-1 antagonize morphine and opioid but not non-opioid stress-induced analgesia in the snail, Cepaea nemoralis.
Peptides. 1987 Jan-Feb;8(1):1-5. doi: 10.1016/0196-9781(87)90155-0.
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Study on the antinociceptive action of Tyr-K-MIF-1, a peptide from the MIF family.
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A Tyr-W-MIF-1 analog containing D-Pro2 acts as a selective mu2-opioid receptor antagonist in the mouse.
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Cimetidine does not change the effect of Tyr-MIF-1 (Tyr-Pro-Leu-Gly-NH2) on the opiate form of footshock-induced analgesia.
Life Sci. 1991;49(16):1163-8. doi: 10.1016/0024-3205(91)90563-q.
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Intrathecal Tyr-W-MIF-1 produces potent, naloxone-reversible analgesia modulated by alpha 2-adrenoceptors.
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Analgesic effects of Tyr-W-MIF-1: a mixed mu2-opioid receptor agonist/mu1-opioid receptor antagonist.
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Repeated administration of naltrexone produces tolerance to naloxone-induced hyperalgesia.
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Opiate-like effects of electroconvulsive shock in rats: a differential effect of naloxone on nociceptive measures.
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Stress-induced analgesia: neural and hormonal determinants.
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Conditioned morphine tolerance in the rat: absence of a compensatory response and cross-tolerance with stress.
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Naloxone hyperalgesia and stress-induced analgesia in rats.
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Comparisons between warm and cold water swim stress in mice.
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Intrinsic mechanisms of pain inhibition: activation by stress.
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Pain modulation by 5-hydroxytryptaminergic agents and morphine as measured by three pain tests.
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Effect of environmental novelty and electroconvulsive shock on the tail flick reflex after placebo or morphine pellet implants.
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A comparison of antinociception induced by foot shock and morphine.
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