Wen Si, Guan Xi-Feng, Huang Xiao-Jun, Fan Chun-Lin, Ye Wen-Cai, Wang Ying
Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China.
JNU-HKUST Joint Laboratory for Neuroscience & Innovative Drug Research, Jinan University, Guangzhou 510632, China.
Zhongguo Zhong Yao Za Zhi. 2017 Jul;42(13):2503-2509. doi: 10.19540/j.cnki.cjcmm.20170512.005.
A new δ-oleanane-type triterpenoid glycoside, 3-O-(3-O-sulfo)-β-D-glucopyranosiduronic acid 3β-hydroxy-13(18)-oleanen- 28-oic acid 28-β-D-glucopyranosyl ester (1), along with ten known triterpenoid glycosides, rotundinoside A (2), oblonganoside M (3), 3-O-β-D-glucopyranosyl-(1→2)-α-L-arabinopyranosyl 3β,19α-dihydroxy-20α- urs-12-en-28-oic acid 28-O-β-D- glucopyranosyl ester (4), ilexsaponin B2 (5), ilexside Ⅱ (6), rotundinoside B (7), ilekudinoside B (8), ilexpublesnin E (9), ilekudinoside D (10) and ilexpernoside D (11), was isolated from the 75% ethanol extract of the roots of Ilex asprella by various chromatographic separation. Their structures were identified on the basis of MS, NMR spectroscopic analysis and chemical methods. In addition, 2-11 were isolated from I. asprella for the first time.
从岗梅根的75%乙醇提取物中，通过各种色谱分离方法，分离得到了一种新的齐墩果烷型三萜糖苷，3 - O -（3 - O - 磺基）-β - D - 吡喃葡萄糖醛酸3β - 羟基 - 13（18）- 齐墩果烯 - 28 - 酸28 - β - D - 吡喃葡萄糖基酯（1），以及十种已知的三萜糖苷，轮环藤宁苷A（2）、长梗冬青苷M（3）、3 - O - β - D - 吡喃葡萄糖基 -（1→2）-α - L - 阿拉伯吡喃糖基3β，19α - 二羟基 - 20α - 乌苏 - 12 - 烯 - 28 - 酸28 - O - β - D - 吡喃葡萄糖基酯（4）、冬青皂苷B2（5）、冬青苷Ⅱ（6）、轮环藤宁苷B（7）、岗梅皂苷B（8）、毛冬青皂苷E（9）、岗梅皂苷D（10）和毛冬青皂苷D（11）。通过质谱、核磁共振光谱分析和化学方法确定了它们的结构。此外，2 - 11首次从岗梅中分离得到。
