Kojima Keisuke, S Purevsuren, S Narantuya, S Tsetsegmaa, Ya Jamyansan, Lsaka Kimio, Ogihara Yukio
Faculty of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe Dori, Mizuho-ku, Nagoya 467, Japan.
Depart. of Pharmacy, Mongolian Medical University, Ulaanbaatar-3, Mongolia.
Sci Pharm. 2017 Aug 25;69(4):680-685. doi: 10.3797/scipharm.aut-01-208.
Five alkaloids were isolated from the epigeal part of Oxytropis myriophylla. Three alkaloids were identified as N-benzoyl-β-phenylethylamine, N-trans-cinnamoyl-β-phenylethylamine, N-cis-cinnamoyl-β-phenylethylamine and the structures of two new alkaloids were elucidated to be N-benzoyl-β-hydroxyphenylethylarnine(2), N-trans-cinnamoyl-β-hydroxy-phenylethylamine(5). The absolu.te structures were established by modified Mosher method.
从多叶棘豆地上部分分离得到5种生物碱。其中3种生物碱被鉴定为N-苯甲酰基-β-苯乙胺、N-反式肉桂酰基-β-苯乙胺、N-顺式肉桂酰基-β-苯乙胺,另外两种新生物碱的结构被确认为N-苯甲酰基-β-羟基苯乙胺(2)、N-反式肉桂酰基-β-羟基苯乙胺(5)。其绝对构型通过改进的莫舍尔方法确定。