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寨卡病毒疫情并发症在扩大预防和控制策略方面的伦理、法律及社会考量

Ethical, legal and societal considerations on Zika virus epidemics complications in scaling-up prevention and control strategies.

作者信息

Tambo Ernest, Madjou Ghislaine, Khayeka-Wandabwa Christopher, Olalubi Oluwasogo A, Chengho Chryseis F, Khater Emad I M

机构信息

Department Biochemistry and Pharmaceutical Sciences, Higher Institute of Health Sciences, Université des Montagnes, Bangangté, Cameroon.

Africa Disease Intelligence and Surveillance, Communication and Response (Africa DISCoR) Institute, Yaoundé, Cameroon.

出版信息

Philos Ethics Humanit Med. 2017 Aug 25;12(1):3. doi: 10.1186/s13010-017-0046-8.

Abstract

Much of the fear and uncertainty around Zika epidemics stem from potential association between Zika virus (ZIKV) complications on infected pregnant women and risk of their babies being born with microcephaly and other neurological abnormalities. However, much remains unknown about its mode of transmission, diagnosis and long-term pathogenesis. Worries of these unknowns necessitate the need for effective and efficient psychosocial programs and medical-legal strategies to alleviate and mitigate ZIKV related burdens. In this light, local and global efforts in maintaining fundamental health principles of moral, medical and legal decision-making policies, and interventions to preserve and promote individual and collectiveHuman Rights, autonomy, protection of the most vulnerable, equity, dignity, integrity and beneficence that should not be confused and relegated by compassionate humanitarian assistance and support. This paper explores the potential medical and ethical-legal implications of ZIKV epidemics emergency response packages and strategies alongside optimizing reproductive and mental health policies, programs and best practice measures. Further long-term cross-borders operational research is required in elucidating Zika-related population-based epidemiology, ethical-medical and societal implications in guiding evidence-based local and global ZIKV maternal-child health complications related approaches and interventions. Core programs and interventions including future Zika safe and effective vaccines for global Zika immunization program in most vulnerable and affected countries and worldwide should be prioritized.

摘要

围绕寨卡疫情的许多恐惧和不确定性源于寨卡病毒(ZIKV)感染孕妇后出现的并发症与其婴儿患小头畸形及其他神经异常风险之间的潜在关联。然而,关于其传播方式、诊断及长期发病机制仍有许多未知之处。对这些未知因素的担忧使得有必要制定有效且高效的社会心理项目及医疗法律策略,以减轻和缓解与寨卡病毒相关的负担。有鉴于此,地方和全球层面在维护道德、医疗和法律决策政策等基本健康原则方面所做的努力,以及为维护和促进个人及集体人权、自主权、保护最弱势群体、公平、尊严、完整和仁爱而采取的干预措施,不应因同情性的人道主义援助和支持而被混淆或贬低。本文探讨了寨卡病毒疫情应急方案和策略在优化生殖与心理健康政策、项目及最佳实践措施方面的潜在医学和伦理法律影响。为阐明与寨卡相关的基于人群的流行病学、伦理医学及社会影响,以指导基于证据的地方和全球寨卡病毒母婴健康并发症相关方法及干预措施,还需要进一步开展长期跨境行动研究。应优先考虑核心项目和干预措施,包括为全球最脆弱和受影响国家及全球范围内的寨卡免疫计划研发未来安全有效的寨卡疫苗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0acd/5574124/4788502ee128/13010_2017_46_Fig1_HTML.jpg

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