Department of Public Health and Clinical Medicine, Epidemiology and Global Health, Umeå University, Umeå, Sweden.
Department of Social Sciences, Umeå University, Umeå, Sweden.
Arch Dis Child. 2018 Feb;103(2):143-148. doi: 10.1136/archdischild-2017-312830. Epub 2017 Aug 26.
Coeliac disease might affect school performance due to its effect on cognitive performance and related health consequences that might increase school absenteeism. The aim of this study was to investigate whether children with coeliac disease performed differently on completion of ninth grade in school compared with children without coeliac disease.
Analysis was performed on a population of 445 669 children born in Sweden between 1991 and 1994 of whom 1767 were diagnosed with coeliac disease. School performance at ninth grade was the outcome and coeliac disease was the exposure. Other covariates included sex, Apgar score at 5 min, small for gestational age, year of birth, family type, parental education and income.
There was no association between coeliac disease and school performance at ninth grade (adjusted coefficient -2.4, 95% CI 5.1 to 0.4). A weak association was established between late coeliac diagnosis and higher grades, but this disappeared after adjusting for parent socioeconomic conditions. Being small for gestational age affected performance negatively (adjusted coefficient -6.9, 95% CI 8.0 to 5.7). Grade scores were significantly lower in children living with a single parent (adjusted coefficient -20.6, 95% CI 20.9 to 20.2), compared with those with married/cohabiting parents. A positive association was found between scores at ninth grade and parental education and income.
Coeliac disease diagnosis during childhood is not associated with poor school performance at ninth grade.
乳糜泻可能会影响学业表现，因为它会影响认知表现，以及可能导致更高的缺课率的相关健康后果。本研究旨在调查乳糜泻儿童在完成九年级学业时的表现是否与非乳糜泻儿童不同。
对 1991 年至 1994 年间在瑞典出生的 445669 名儿童进行了一项人群分析，其中 1767 名被诊断患有乳糜泻。九年级的学业成绩是结局，乳糜泻是暴露因素。其他协变量包括性别、5 分钟时的阿普加评分、小于胎龄儿、出生年份、家庭类型、父母教育程度和收入。
乳糜泻与九年级学业成绩之间无关联（调整后的系数-2.4，95%CI5.1 至 0.4）。乳糜泻的晚期诊断与更高的成绩之间存在微弱关联，但在调整父母社会经济状况后，这种关联消失了。小于胎龄儿的表现则呈负相关（调整后的系数-6.9，95%CI8.0 至 5.7）。与有父母一方的家庭相比，与父母一方的家庭相比，与已婚/同居父母的家庭相比，与单亲家庭的孩子的成绩分数显著较低（调整后的系数-20.6，95%CI20.9 至 20.2）。与父母的教育程度和收入呈正相关。
儿童期乳糜泻的诊断与九年级学业成绩不佳无关。
