Mazzarello Vittorio, Ferrari Marco, Bulla Antonio, Piu Gabriella, Montella Andrea
Department of Biomedical Sciences, University of Sassari, Sassari, Italy.
Department of Surgical, Microsurgical and Medical Sciences, University of Sassari, Sassari, Italy.
J Cosmet Dermatol. 2018 Jun;17(3):484-490. doi: 10.1111/jocd.12395. Epub 2017 Aug 28.
Adhesive pads should reduce the action of the local muscle contraction on the skin leading to a decrease in the depth of existing wrinkles and the formation of new dynamic wrinkles.
This study aims at assessing the antiwrinkles action of adhesive pads during time, and the temporary improvement of facial skin appearance by reducing the vision of linear wrinkles and improving skin elasticity.
Thirty-nine subjects participated to a placebo-controlled study. In the short-term test, the measurements were taken 15, 30, and 60 minutes following 30 minutes application of the product; in the long-term test, the measurements were taken after wearing pads every night for 4 weeks. The roughness parameter of the skin surface was calculated by using a profilometry software 3D MEX .
In the short- and long-term tests, analyzing the average of the elastomeric measurements, no significant change was observed in any of the parameters analyzed after 15, 30, and 60 minutes. The adhesive pad decreased significantly all roughness skin parameters 15 minutes after short-term application and until 60 minutes after long-term application. These changes did not occur in the contralateral untreated zone.
The use of topical adhesive pads improves wrinkles in the crow's feet area in the first hour after use. However, patient self-evaluation indicated that the use of topical adhesive pads for 3 weeks may offer subjective improvement in crow's feet zone over a 2 hour period. Topical adhesive pads are safe to use and tolerable for most users.
粘性贴片应能减少局部肌肉收缩对皮肤的作用,从而减少现有皱纹的深度并防止新的动态皱纹形成。
本研究旨在评估粘性贴片随时间的抗皱作用,以及通过减少线性皱纹的视觉效果和改善皮肤弹性来暂时改善面部皮肤外观。
39名受试者参与了一项安慰剂对照研究。在短期测试中,在涂抹产品30分钟后的15、30和60分钟进行测量;在长期测试中,在每晚佩戴贴片4周后进行测量。使用轮廓测定软件3D MEX计算皮肤表面的粗糙度参数。
在短期和长期测试中,分析弹性测量的平均值,在15、30和60分钟后分析的任何参数中均未观察到显著变化。粘性贴片在短期应用15分钟后以及长期应用直至60分钟后,显著降低了所有皮肤粗糙度参数。对侧未处理区域未出现这些变化。
使用局部粘性贴片在使用后的第一小时可改善鱼尾纹区域的皱纹。然而,患者自我评估表明,使用局部粘性贴片3周可能在2小时内使鱼尾纹区域有主观改善。局部粘性贴片使用安全,大多数使用者可耐受。