Menon Gopal, Mukkamalla Shiva Kumar R.
Presbyterian Healthcare Services
Mucinous cystic pancreatic neoplasms (MCPNs) are mucin-producing cystic lesions of the exocrine pancreas, usually located in the pancreatic body and tail. While mostly benign, MCPNs can harbor foci of dysplasia and progress to invasive adenocarcinoma. MCPNs must be differentiated from other pancreatic cystic lesions, including benign entities such as serous cystadenomas and premalignant lesions such as intraductal pancreatic mucinous neoplasms. MCPNs are often asymptomatic and incidental findings on cross-sectional imaging. Improvements in diagnostic imaging and endoscopic techniques have increased the accuracy of diagnosis of MCPNs and helped clinicians formulate appropriate treatment plans. Given their malignant potential, all MCPNs should be excised in patients fit to undergo surgery. This activity will review the epidemiology, etiology, pathophysiology, histologic characteristics, clinical presentation, evaluation, and management of patients with MCPNs and highlight the role of the interprofessional team caring for patients with these pancreatic lesions.
黏液性囊性胰腺肿瘤（MCPNs）是外分泌胰腺产生黏液的囊性病变，通常位于胰体和胰尾。虽然大多为良性，但MCPNs可含有发育异常灶并进展为浸润性腺癌。MCPNs必须与其他胰腺囊性病变相鉴别，包括良性实体如浆液性囊腺瘤和癌前病变如导管内乳头状黏液性肿瘤。MCPNs通常无症状，是在横断面成像时偶然发现的。诊断性成像和内镜技术的进步提高了MCPNs的诊断准确性，并有助于临床医生制定合适的治疗方案。鉴于其恶性潜能，所有适合手术的MCPNs患者均应行手术切除。本活动将回顾MCPNs患者的流行病学、病因、病理生理学、组织学特征、临床表现、评估和管理，并强调跨专业团队在护理这些胰腺病变患者中的作用。
