Farooq Zerwa, Behzadi Ashkan Heshmatzadeh, Blumenfeld Jon D, Zhao Yize, Prince Martin R
Department of Radiology, Weill Cornell Medical Center, New York, NY, United States.
The Rogosin Institute, United States; Division of Nephrology, Hypertenson, and Transplant Medicine, Department of Medicine, Weill Cornell Medical Center, United States.
Clin Imaging. 2018 Jan-Feb;47:41-46. doi: 10.1016/j.clinimag.2017.07.004. Epub 2017 Jul 12.
To compare MRI segmentation methods for measuring liver cyst volumes in autosomal dominant polycystic kidney disease (ADPKD).
Liver cyst volumes in 42 ADPKD patients were measured using region growing, thresholding and cyst diameter techniques. Manual segmentation was the reference standard.
Root mean square deviation was 113, 155, and 500 for cyst diameter, thresholding and region growing respectively. Thresholding error for cyst volumes below 500ml was 550% vs 17% for cyst volumes above 500ml (p<0.001).
For measuring volume of a small number of cysts, cyst diameter and manual segmentation methods are recommended. For severe disease with numerous, large hepatic cysts, thresholding is an acceptable alternative.
比较用于测量常染色体显性多囊肾病（ADPKD）患者肝囊肿体积的MRI分割方法。
采用区域生长法、阈值法和囊肿直径法测量42例ADPKD患者的肝囊肿体积。手动分割作为参考标准。
囊肿直径法、阈值法和区域生长法的均方根偏差分别为113、155和500。囊肿体积小于500ml时阈值法误差为550%，而囊肿体积大于500ml时为17%（p<0.001）。
对于测量少量囊肿的体积，推荐使用囊肿直径法和手动分割法。对于有大量大肝囊肿的严重疾病，阈值法是一种可接受的替代方法。
