Persson J, Magnusson P H
Scand J Prim Health Care. 1987 Feb;5(1):13-23. doi: 10.3109/02813438709024181.
In this study of 1985 patients in somatic outpatient care (medicine, surgery, orthopedics, emergency and primary health care clinics), 231, or 11.6%, were found to have an elevated serum GT value (above 0.9 mukat/l). Alcohol was the cause of this in approximately one third of the cases, while diseases and drugs were the underlying cause in the other cases. In the population, there were 208 alcohol-overconsuming patients (163 men and 45 women) and 28 patients had a serum GT elevation which led to detection of a previous unknown alcohol problem or excessive consumption. The mean and median value for serum GT for the alcohol patients was markedly higher than in the non-alcohol-overconsuming group. The sensitivity for serum GT (with a value of 0.9) as regards alcohol consumption was 40%. The GT test screened 4.2% of patients with excessive alcohol consumption of which one third were "hidden".
在这项针对1985名躯体门诊患者(来自内科、外科、骨科、急诊科和初级卫生保健诊所)的研究中,发现231名患者(占11.6%)血清γ-谷氨酰转移酶(GT)值升高(高于0.9微卡/升)。其中约三分之一的病例是由酒精引起的,而其他病例的潜在病因是疾病和药物。在总体人群中,有208名饮酒过量患者(163名男性和45名女性),28名患者血清GT升高,这导致发现了先前未知的酒精问题或饮酒过量情况。酒精患者的血清GT均值和中位数明显高于非饮酒过量组。血清GT值为0.9时,对酒精消费的敏感度为40%。GT检测筛查出4.2%的饮酒过量患者,其中三分之一为“隐性”患者。