β受体阻滞剂及其他抗心律失常药物的围手术期管理
Perioperative Management of Beta Blockers and Other Antiarrhythmic Medications.
作者信息
Irizarry-Alvarado Joan M
机构信息
Department of General Internal Medicine, Mayo Clinic, Jacksonville, FL 32224, United States.
出版信息
Curr Clin Pharmacol. 2017;12(3):141-144. doi: 10.2174/1574884712666170829114820.
BACKGROUND
Antiarrhythmic medications are an important tool in preventing recurrence of intraoperative and postoperative arrhythmias.
OBJECTIVE
To review current literature and recommendations for perioperative management of antiarrhythmic medications.
METHODS
Literature review is presented along with the pharmacology of antiarrhythmics.
RESULTS
Antiarrhythmic medications should be continued perioperatively for the prevention of arrhythmias intra- and postoperatively. However, beta blockers have had controversies regarding their perioperative safety profile.
CONCLUSION
Continuation of antiarrhythmic medications is safe perioperatively. However, initiation of beta blockers should be patient-tailored and titrated to a target heart rate in advance surgery.
背景
抗心律失常药物是预防术中及术后心律失常复发的重要工具。
目的
回顾抗心律失常药物围手术期管理的当前文献及建议。
方法
结合抗心律失常药物的药理学进行文献综述。
结果
抗心律失常药物应在围手术期持续使用以预防术中和术后心律失常。然而，β受体阻滞剂在围手术期安全性方面存在争议。
结论
抗心律失常药物在围手术期持续使用是安全的。然而，β受体阻滞剂的起始使用应根据患者情况进行调整，并在术前滴定至目标心率。
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