Hockenhull Jo, Turner Andrea E, Reyher Kristen K, Barrett David C, Jones Laura, Hinchliffe Stephen, Buller Henry J
School of Veterinary Sciences, University of Bristol, Bristol, UK.
College of Life and Environmental Sciences, University of Exeter, Exeter, UK.
Vet Rec. 2017 Nov 11;181(19):510. doi: 10.1136/vr.104304. Epub 2017 Aug 28.
Food-producing animals throughout the world are likely to be exposed to antimicrobial (AM) treatment. The crossover in AM use between human and veterinary medicine raises concerns that antimicrobial resistance (AMR) may spread from food-producing animals to humans, driving the need for further understanding of how AMs are used in livestock practice as well as stakeholder beliefs relating to their use. A rapid evidence assessment (REA) was used to collate research on AM use published in peer-reviewed journals between 2000 and 2016. Forty-eight papers were identified and reviewed. The summary of findings highlights a number of issues regarding current knowledge of the use of AMs in food-producing animals and explores the attitudes of interested parties regarding the reduction of AM use in livestock. Variation between and within countries, production types and individual farms demonstrates the complexity of the challenge involved in monitoring and regulating AM use in animal agriculture. Many factors that could influence the prevalence of AMR in livestock are of concern across all sections of the livestock industry. This REA highlights the potential role of farmers and veterinarians and of other advisors, public pressure and legislation to influence change in the use of AMs in livestock.
全球范围内的食用动物都可能会接受抗菌药物治疗。人畜医学中抗菌药物使用的交叉引发了人们的担忧，即抗菌药物耐药性可能会从食用动物传播给人类，这促使人们需要进一步了解抗菌药物在畜牧实践中的使用情况以及利益相关者对其使用的看法。一项快速证据评估（REA）被用于整理2000年至2016年间发表在同行评审期刊上的关于抗菌药物使用的研究。共识别并评审了48篇论文。研究结果总结突出了一些关于目前食用动物抗菌药物使用知识的问题，并探讨了相关各方对减少畜牧抗菌药物使用的态度。国家之间、生产类型之间以及各个农场之间的差异表明，监测和规范动物农业中抗菌药物使用所涉及的挑战十分复杂。许多可能影响畜牧抗菌药物耐药性流行率的因素在畜牧行业的各个领域都受到关注。这项快速证据评估突出了农民、兽医以及其他顾问、公众压力和立法在影响畜牧抗菌药物使用变化方面的潜在作用。
