Jahja Elvina J, Yuliana Riana, Simanjuntak Welinda Turianna, Fitriya Noer, Rahmawati Anita, Yulinah Elin
Animal Health Research & Development, Medion Farma Jaya, Jalan Raya Batujajar 29, Bandung, West Java 40552, Indonesia.
Department of Pharmacology and Clinical Pharmacy, Bandung Institute of Technology (ITB), Indonesia.
Vet Anim Sci. 2022 Nov 30;19:100274. doi: 10.1016/j.vas.2022.100274. eCollection 2023 Mar.
The objective of this study was to investigate the effect of phytobiotics combination of and water extracts (FOA) mixed into the feed of broiler and specific-pathogen-free chickens as an alternative to Antibiotics Growth Promoter (AGP). Performance, intestinal bacteria characteristic, and oocysts of spp. in feces were measured and compared with the AGP-added group. The first experiment in broiler chickens compared FOA, Zinc Bacitracin (ZB, as an AGP group), and negative control. On day 28, FOA group and ZB group showed significantly higher body weight than the control group ( < 0.05). The FCR of ZB group was better than FOA group. However, FOA group displayed better microbiota profile than ZB group and negative control, with more sppnd spp., and less and spp. isolated from intestines. The second experiment in specific-pathogen-free chickens showed the anticoccidial effect of FOA addition to reduce the number of oocysts per gram (OPG) from live coccidia vaccine. FOA group and Amprolium group showed OPG reduction (82.53% and 92.02%, respectively) after 7 days of treatment. In conclusion, the combination of and extract can function as an AGP replacement in feed.
本研究的目的是调查将植物源生物制剂组合（和水提取物，简称FOA）混入肉鸡和无特定病原体鸡的饲料中作为抗生素生长促进剂（AGP）替代品的效果。测定了生产性能、肠道细菌特征以及粪便中球虫属的卵囊，并与添加AGP的组进行了比较。肉鸡的第一个实验比较了FOA、杆菌肽锌（ZB，作为AGP组）和阴性对照。在第28天，FOA组和ZB组的体重显著高于对照组（P<0.05）。ZB组的饲料转化率优于FOA组。然而，FOA组的微生物群谱比ZB组和阴性对照更好，从肠道分离出的双歧杆菌属和乳酸杆菌属更多，而大肠杆菌和沙门氏菌属更少。无特定病原体鸡的第二个实验显示，添加FOA具有抗球虫作用，可减少活球虫疫苗每克粪便中的卵囊数（OPG）。治疗7天后，FOA组和氨丙啉组的OPG均有所降低（分别为82.53%和92.02%）。总之，和提取物的组合可作为饲料中AGP的替代品发挥作用。
