Cozanitis D A, Hofmockel R, Benad G, Sitarek U
Acta Anaesthesiol Belg. 1987;38(1):77-81.
In order to compare tracheal intubation conditions, 34 adult patients about to undergo elective surgery received at random atracurium 0.5 mg X kg-1, pipecuronium 0.1 mg X kg-1 or vecuronium 0.1 mg X kg-1, intravenously. Intubation was attempted when only the first of the train-of-four finger contractions, arising from ulnar nerve stimulation, remained. The three relaxants provided effective conditions for intubation. The time required to suppress all but the first train-of-four response was shortest in the group given atracurium (P less than 0.05). Compound muscle action potentials (emg) were continuously filmed from just before induction of anesthesia until the trachea was intubated. The degree of neuromuscular blockade was similar in the three study groups.
为比较气管插管条件，34例即将接受择期手术的成年患者随机静脉注射阿曲库铵0.5mg/kg、哌库溴铵0.1mg/kg或维库溴铵0.1mg/kg。当尺神经刺激引起的四个成串刺激中仅保留第一个手指收缩时尝试插管。三种肌松药均提供了有效的插管条件。在给予阿曲库铵的组中，抑制除第一个四个成串刺激反应外所有反应所需时间最短（P<0.05）。从麻醉诱导前直至气管插管，持续拍摄复合肌肉动作电位（肌电图）。三个研究组的神经肌肉阻滞程度相似。
