Gross E M, Yagupsky P
Acta Trop. 1987 Mar;44(1):91-6.
We observed and recorded clinical and laboratory data from 54 children with fever and a maculo-papular rash admitted to Soroka Medical Center, Beersheva, Israel suffering from serologically confirmed rickettsial spotted fever. The rash generally began on the palms and soles and extended centripetally to the torso. Other clinical findings included myalgia, headache, hepatomegaly, and splenomegaly. None had a "tache noire". A left shift in the white cells, leucopenia, thrombocytopenia, hyponatraemia and impaired liver function tests were common laboratory abnormalities. All recovered following oral doxycycline therapy. Serious sequelae such as myocarditis, encephalitis, and disseminated intravascular coagulation, as reported in Rocky Mountain spotted fever, did not occur.
我们观察并记录了54名因血清学确诊为立克次体斑疹热而入住以色列贝尔谢巴索罗卡医疗中心的发热伴斑丘疹儿童的临床和实验室数据。皮疹通常始于手掌和脚底，并向心性扩展至躯干。其他临床发现包括肌痛、头痛、肝肿大和脾肿大。无人出现“黑色斑点”。白细胞左移、白细胞减少、血小板减少、低钠血症和肝功能检查异常是常见的实验室异常情况。所有患者经口服强力霉素治疗后均康复。落基山斑疹热所报道的心肌炎、脑炎和弥散性血管内凝血等严重后遗症未发生。
