乙酰丙嗪、地西泮、氟哌利多-芬太尼和羟吗啡酮对健康犬胃食管括约肌压力的影响。
Effect of acepromazine, diazepam, fentanyl-droperidol, and oxymorphone on gastroesophageal sphincter pressure in healthy dogs.
作者信息
Hall J A, Magne M L, Twedt D C
出版信息
Am J Vet Res. 1987 Apr;48(4):556-7.
PMID:2884907
Abstract
Treatment of healthy dogs with 4 commonly used psychotropic or analgesic agents significantly decreased resting gastroesophageal sphincter pressure (GESP). Acepromazine decreased GESP by 35% (P = 0.02); oxymorphone decreased GESP by 38% (P less than 0.005); diazepam decreased GESP by 42% (P = 0.005); and fentanyl-droperidol decreased GESP by 40% (P = 0.03). Therefore, esophageal manometric evaluation of gastroesophageal sphincter function should not be preceded by administration of these drugs.
摘要
用4种常用的精神类或镇痛类药物治疗健康犬，可显著降低静息时的胃食管括约肌压力（GESP）。乙酰丙嗪使GESP降低35%（P = 0.02）；羟吗啡酮使GESP降低38%（P < 0.005）；地西泮使GESP降低42%（P = 0.005）；芬太尼-氟哌利多使GESP降低40%（P = 0.03）。因此，在进行食管测压评估胃食管括约肌功能之前，不应给予这些药物。
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