Lambertini Carlotta, Pietra Marco, Galiazzo Giorgia, Torresan Francesco, Pinna Stefania, Pisoni Luciano, Romagnoli Noemi
Department of Veterinary Medical Sciences, University of Bologna, Italy. Via Tolara di Sopra 50, 40064 Ozzano dell'Emilia (BO), Italy.
Department of Digestive System, St. Orsola-Malpighi Hospital, Via Massarenti, 40100 Bologna, Italy.
Vet Sci. 2020 Sep 25;7(4):144. doi: 10.3390/vetsci7040144.
Gastroesophageal reflux (GER) is a common event during general anaesthesia but is often underdiagnosed in veterinary medicine. The oesophageal pH in anaesthetised dogs undergoing endoscopic evaluation of the upper gastrointestinal tract (END group; = 12) or orthopaedic surgery (ORT group; = 12) was measured using an oesophageal probe. The dogs were sedated with acepromazine or with methadone or butorphanol, and anaesthesia was induced with propofol and maintained with isoflurane. Of the 24 dogs in this study, 21 (87.5%) had an episode of GER during anaesthesia. The incidence of GER, as well as the first, the minimum, and the maximum pH values, did not differ significantly between the groups. The mean maximum difference versus the first pH value was higher for dogs in the END group (-2.6 ± 3.5) as compared with those in the ORT group (-0.7 ± 2.5), although they were not statistically significant ( = 0.25). The administration of methadone or butorphanol had no significant effect on the development of acidic reflux or biliary reflux. In the acepromazine-sedated dogs, the incidence of GER did not differ significantly between patients undergoing an endoscopic procedure and those undergoing orthopaedic surgery; however, during endoscopy, fluctuations in the oesophageal pH can be expected, even without any clinical signs of GER.
胃食管反流(GER)是全身麻醉期间的常见事件,但在兽医学中常被漏诊。使用食管探头测量接受上消化道内镜评估的麻醉犬(内镜组;n = 12)或骨科手术的麻醉犬(骨科组;n = 12)的食管pH值。犬只使用乙酰丙嗪或美沙酮或布托啡诺进行镇静,丙泊酚诱导麻醉,异氟烷维持麻醉。在本研究的24只犬中,21只(87.5%)在麻醉期间发生了GER事件。两组之间的GER发生率以及首次、最低和最高pH值没有显著差异。内镜组犬的平均最大差异与首次pH值相比高于骨科组犬(-2.6±3.5)与(-0.7±2.5),尽管差异无统计学意义(P = 0.25)。美沙酮或布托啡诺的给药对酸性反流或胆汁反流的发生没有显著影响。在使用乙酰丙嗪镇静的犬中,接受内镜检查的患者和接受骨科手术的患者之间的GER发生率没有显著差异;然而,在内镜检查期间,即使没有任何GER的临床体征,食管pH值也可能会波动。