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基于社区的干预措施(包括每月发放定量配给食品)对接受抗逆转录病毒治疗第一年的 HIV 阳性成年人的粮食不安全状况的影响。

The Impact of a Community-Based Intervention Including a Monthly Food Ration on Food Insecurity Among HIV-Positive Adults During the First Year of Antiretroviral Therapy.

机构信息

American University, Washington, DC, USA.

Ruhengeri Hospital, Republic of Rwanda Ministry of Health, Kigali, Rwanda.

出版信息

AIDS Behav. 2018 Jan;22(1):154-163. doi: 10.1007/s10461-017-1897-0.

Abstract

The objective of this study was to examine how food insecurity changed among HIV-positive adults during the first 12 months of combination antiretroviral therapy (cART) and whether any change differed according to the receipt of food support, which was provided in the context of a comprehensive community-based intervention. We conducted secondary data analyses of data from a prospective cohort study of the effectiveness of a community-based cART delivery model when added to clinic-based cART delivery in Rwanda. We included patients from four health centers that implemented a clinic-based cART delivery model alone and five health centers that additionally implemented the intervention, which included 10 months of food support. We compared food insecurity at 3, 6, and 12 months, relative to baseline, and stratified by receipt of the intervention. Relative to baseline, median food insecurity score decreased after 3, 6, and 12 months (p value <0.0001 for all) for patients receiving a food ration through the community-based model for cART delivery. Among patients receiving care under the clinic-based cART model, food insecurity scores remained unchanged at 3 and 12 months and were significantly higher after 6 months. In adjusted analyses, participants enrolled in the community-based intervention with a food ration had a lower risk of severe food insecurity and a lower risk of moderate or severe food insecurity after 12 months. A comprehensive community-based HIV program including a food ration likely contributes to an alleviation of food insecurity among adults newly initiating cART.

摘要

本研究旨在探讨在接受联合抗逆转录病毒疗法(cART)的前 12 个月期间,艾滋病毒阳性成年人的粮食不安全状况如何变化,以及在接受粮食支持的情况下,这种变化是否有所不同,而粮食支持是在一个综合社区为基础的干预措施背景下提供的。我们对一项前瞻性队列研究的数据进行了二次数据分析,该研究评估了在卢旺达将基于社区的 cART 提供模式添加到诊所为基础的 cART 提供模式时的效果。我们纳入了来自四个单独实施诊所为基础的 cART 提供模式的卫生中心的患者和五个额外实施包括 10 个月粮食支持的干预措施的卫生中心的患者。我们比较了 3 个月、6 个月和 12 个月相对于基线时的粮食不安全状况,并根据干预措施的接受情况进行分层。与基线相比,接受社区为基础的 cART 提供模式的粮食配给的患者在 3 个月、6 个月和 12 个月后(所有 p 值均<0.0001),其粮食不安全评分中位数均下降。在接受诊所为基础的 cART 模型治疗的患者中,3 个月和 12 个月时粮食不安全评分保持不变,而 6 个月时显著升高。在调整分析中,参加基于社区的干预措施并获得粮食配给的参与者在 12 个月后发生严重粮食不安全的风险较低,且发生中度或严重粮食不安全的风险也较低。一个包括粮食配给的综合社区艾滋病毒方案可能有助于缓解新开始接受 cART 的成年人的粮食不安全状况。

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