Kalscheuer H, Serfling G, Schmid S, Lehnert H
Medizinische Klinik I, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Deutschland.
Präsidium der Universität zu Lübeck, Universität zu Lübeck, Lübeck, Deutschland.
Internist (Berl). 2017 Oct;58(10):1020-1028. doi: 10.1007/s00108-017-0317-x.
The diabetic emergencies diabetic ketoacidosis (DKA), hyperglycemic hyperosmolar state (HHS) and hypoglycemia represent severe and potentially life-threatening complications of diabetes mellitus that require prompt diagnostics and treatment. Absolute or relative insulin insufficiency is characteristic of DKA und HHS along with severe dehydration. They differ by the prevalence of ketone bodies and the severity of acidosis; however, the treatment regimens are similar. In contrast, hypoglycemia is the limiting factor for achieving ambitious glucose targets. This article decribes the clinical presentation, diagnostics and emergency management of these metabolic derangements.
糖尿病急症包括糖尿病酮症酸中毒(DKA)、高血糖高渗状态(HHS)和低血糖,是糖尿病严重且可能危及生命的并发症,需要及时诊断和治疗。DKA和HHS的特点是绝对或相对胰岛素不足以及严重脱水。它们在酮体的发生率和酸中毒的严重程度上有所不同;然而,治疗方案相似。相比之下,低血糖是实现严格血糖目标的限制因素。本文描述了这些代谢紊乱的临床表现、诊断和紧急处理。