Bao Tongzhu, Han Fang, Xu Feng, Yang Yi, Shu Xun, Chen Ken, Qi Baiwen, Wei Shijun, Yu Aixi
Department of Orthopedics, Yichang Central People's Hospital and The First Affiliated Hospital of China Three Gorges University, Yichang, 443002, China.
Department of Orthopedics, Wuhan General Hospital, No. 627 Wuluo Road, Hongshan Area, Wuhan, 430070, China.
Int Orthop. 2017 Nov;41(11):2389-2396. doi: 10.1007/s00264-017-3620-1. Epub 2017 Aug 28.
Treatment of open tibial fractures with soft tissue and segmental bone defects is difficult. This study reports our results for treating these injuries with a combination of Papineau open bone grafting and vacuum-assisted wound closure (VAC).
The records of 19 patients with open tibial fractures with soft tissue and segmental bone defects treated with bone grafting and VAC from 2004 to 2010 were retrospectively reviewed. Outcomes included: time to complete granulation tissue coverage, wound healing, and bone union; length of hospitalization; frequency of debridement; number of deep tissue infections.
Initial surgery was performed within 48 hours of injury. Ten fractures were Orthopaedic Trauma Association classification 41-A3, one was 41-C3, seven were 43-A3, and one was 43-C3. No surgical complications occurred, and the mean length of hospitalization was 11.0 ± 3.0 weeks (range, 7-18 weeks). The mean follow-up time was 59.35 ± 8.76 months. The mean time for complete wound healing was 7.76 ± 1.52 weeks (range, 6-11 weeks). Bone union was achieved in all patients at a mean of 33.88 ± 8.37 weeks (range, 23-53 weeks). Only one patient developed a deep tissue infection, which was treated with antibiotics and debridements, and complete bone union wound healing was achieved. Based on Paley grade, five outcomes were excellent, eight were good, and four were fair.
The combination of VAC and open bone grafting results in good outcome for patients with open tibial fractures and severe bone and soft-tissue defects.
治疗伴有软组织和节段性骨缺损的开放性胫骨骨折具有挑战性。本研究报告了我们采用帕皮诺开放植骨术与负压封闭引流术(VAC)联合治疗这些损伤的结果。
回顾性分析2004年至2010年间19例伴有软组织和节段性骨缺损的开放性胫骨骨折患者接受植骨术和VAC治疗的记录。结果包括:完成肉芽组织覆盖的时间、伤口愈合和骨愈合情况;住院时间;清创频率;深部组织感染次数。
受伤后48小时内进行了初次手术。10例骨折为骨科创伤协会(OTA)41 - A3型,1例为41 - C3型,7例为43 - A3型,1例为43 - C3型。未发生手术并发症,平均住院时间为11.0 ± 3.0周(范围7 - 18周)。平均随访时间为59.35 ± 8.76个月。伤口完全愈合的平均时间为7.76 ± 1.52周(范围6 - 11周)。所有患者均实现了骨愈合,平均时间为33.88 ± 8.37周(范围23 - 53周)。仅1例患者发生深部组织感染,经抗生素治疗和清创后,实现了完全骨愈合和伤口愈合。根据帕利分级,5例结果为优,8例为良,4例为可。
VAC与开放植骨术联合应用对伴有严重骨和软组织缺损的开放性胫骨骨折患者疗效良好。