Calev A, Korin Y, Kugelmass S, Lerer B
Biol Psychiatry. 1987 Jun;22(6):699-709. doi: 10.1016/0006-3223(87)90201-0.
Matched word and design recall tasks were constructed and used to assess the performance of chronic schizophrenics on neuroleptics alone and on both neuroleptic and anticholinergic drugs. The two groups of patients performed at an equally low level on both tasks, without evidence for a differential deficit. The tasks did, however, evoke a differential deficit in clustering performance for designs as opposed to words. Although clustering, which is based on recall, is not necessarily as well matched for words and designs as recall itself, this result suggests a lateralized dysfunction in brain structures related to use of mnemonic organization at retrieval.
构建了匹配词和图案回忆任务,并用于评估慢性精神分裂症患者单独使用抗精神病药物以及同时使用抗精神病药物和抗胆碱能药物时的表现。两组患者在这两项任务中的表现同样较差,没有证据表明存在差异缺陷。然而,与词相比,这两项任务在图案聚类表现上确实引发了差异缺陷。虽然基于回忆的聚类与词和图案的匹配度不一定像回忆本身那样好,但这一结果表明,在与检索时使用记忆组织相关的脑结构中存在单侧化功能障碍。