精神分裂症中的时间顺序记忆。

Memory for temporal order in schizophrenia.

作者信息

Schwartz B L, Deutsch L H, Cohen C, Warden D, Deutsch S I

机构信息

Department of Psychiatry, VA Medical Center, Washington, DC 20422.

出版信息

Biol Psychiatry. 1991 Feb 15;29(4):329-39. doi: 10.1016/0006-3223(91)90218-b.

DOI:10.1016/0006-3223(91)90218-b

PMID:1674663

Abstract

Memory for temporal order information was examined in patients with chronic schizophrenia using the recency discrimination task. In this task, subjects were shown a pair of previously studied words and were asked to choose which one of the two words they had seen more recently. In addition, subjects performed the Wisconsin Card Sorting Test (WCST). The results showed that schizophrenic patients differed from normal control subjects in their performance on the recency discrimination task. In addition, for schizophrenic patients, performance on the recency discrimination task was inversely related to the number of perseverative errors on the WCST. These results provide further evidence of prefrontal-type cognitive deficits in schizophrenia.

摘要

使用新近度辨别任务对慢性精神分裂症患者的时间顺序信息记忆进行了研究。在该任务中，向受试者展示一对先前学习过的单词，并要求他们选择两个单词中他们最近看到的是哪一个。此外，受试者还进行了威斯康星卡片分类测验（WCST）。结果表明，精神分裂症患者在新近度辨别任务上的表现与正常对照受试者不同。此外，对于精神分裂症患者，新近度辨别任务的表现与WCST上的持续性错误数量呈负相关。这些结果为精神分裂症前额叶型认知缺陷提供了进一步的证据。