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三种新型肥胖指标在监测 2 型糖尿病代谢综合征管理方面表现更好。

Three novel obese indicators perform better in monitoring management of metabolic syndrome in type 2 diabetes.

机构信息

Department of Endocrinology, The First Hospital of Qinhuangdao, No.258 Wenhua Road, Qinhuangdao, 066000, Hebei Province, China.

出版信息

Sci Rep. 2017 Aug 29;7(1):9843. doi: 10.1038/s41598-017-10446-3.

Abstract

The present study evaluated the performance of three novel obese indicators, visceral adiposity index (VAI), lipid accumulation product (LAP) and waist circumference-triglyceride index (WTI), for identifying metabolic syndrome(MetS) in type 2 diabetes. A cross-sectional study was conducted on 711 type 2 diabetes in Qinhuangdao. The MetS was defined as the definition of Chinese Diabetes Society. Receiver operating characteristic curve analyses were performed to assess the accuracy of three obese indicators as diagnostic tests for MetS. The prevalence of MetS was 71.3%. In men, among all three obese indicators, the LAP had the highest area under curve (AUC) value (AUC = 0.894), followed by VAI (AUC = 0.860) and WTI (AUC = 0.855). In women, among all three obese indicators, the LAP had the highest AUC value (AUC = 0.906), followed by WTI (AUC = 0.887) and VAI (AUC = 0.881). However. there was no significant difference between the three obese indicators(P > 0.05). Three obese indicators were effective indicators for the screening of MetS, LAP and WTI are more simple.

摘要

本研究评估了三种新型肥胖指标(内脏脂肪指数[VAI]、脂 肪蓄积产物[LAP]和腰围-甘油三酯指数[WTI])在 2 型糖尿病患者代谢综合征(MetS)识别中的性能。对秦皇岛的 711 例 2 型糖尿病患者进行了横断面研究。MetS 的定义采用中国糖尿病协会的定义。进行受试者工作特征曲线分析,以评估三种肥胖指标作为 MetS 诊断试验的准确性。MetS 的患病率为 71.3%。在男性中,在所有三种肥胖指标中,LAP 的曲线下面积(AUC)值最高(AUC=0.894),其次是 VAI(AUC=0.860)和 WTI(AUC=0.855)。在女性中,在所有三种肥胖指标中,LAP 的 AUC 值最高(AUC=0.906),其次是 WTI(AUC=0.887)和 VAI(AUC=0.881)。然而,三种肥胖指标之间无显著差异(P>0.05)。三种肥胖指标均为 MetS 筛查的有效指标,其中 LAP 和 WTI 更简单。

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