School of Pharmacy, University of Oslo, Oslo, Norway.
Hospital Pharmacies Enterprise, South Eastern Norway, Oslo, Norway.
Spinal Cord. 2018 Jan;56(1):35-40. doi: 10.1038/sc.2017.95. Epub 2017 Aug 29.
A cross-sectional study.
To describe the use of medicines and adherence among persons with spinal cord injury (SCI). Further, to examine the influence of pain, spasms and beliefs about medicines on adherence.
Sunnaas Rehabilitation Hospital, Norway.
Persons (⩾18 years) with chronic SCI (more than 1-year post injury), using at least one drug regularly, and admitted for a follow-up stay at Sunnaas Rehabilitation Hospital were included. Participants were interviewed about their drug regimen and filled out validated self-report questionnaires: Morisky Medication Adherence Scale (MMAS-8), beliefs about medicines questionnaire (BMQ), visual analogue scale (VAS) for pain and modified Penn spasm frequency scale (mPSFS).
The 105 participants used in average 4.2 drugs regularly (range, 1-15), and 70% reported high or moderate adherence to their treatment. Of the 39 participants using oral spasmolytics, 74% reported high or moderate adherence to these drugs. A total of 97% of the participants reported high perceptions of necessity to their treatment and 54% reported a high level of concern.
The persons with SCI included in this study used in average the same number of regular drugs compared to persons with other chronic conditions. Regardless of high overall adherence, the participants were more concerned about their medicines compared to other patient groups. Further studies are required for understanding adherence and attitudes toward medicines in this population, especially to help the persons with chronic SCI feel safe about their drug regimen.
横断面研究。
描述脊髓损伤(SCI)患者的用药情况和用药依从性。此外,还研究疼痛、痉挛和对药物的信念对用药依从性的影响。
挪威 Sunnaas 康复医院。
纳入慢性 SCI(损伤后超过 1 年)、至少定期使用一种药物且因后续治疗入住 Sunnaas 康复医院的患者。对参与者进行了关于其药物治疗方案的访谈,并填写了经过验证的自我报告问卷:Morisky 用药依从性量表(MMAS-8)、药物信念问卷(BMQ)、疼痛视觉模拟量表(VAS)和改良 Penn 痉挛频率量表(mPSFS)。
105 名参与者平均定期使用 4.2 种药物(范围为 1-15 种),70%的参与者报告对其治疗有高度或中度的依从性。在使用口服痉挛药物的 39 名参与者中,74%报告对这些药物有高度或中度的依从性。97%的参与者对其治疗的必要性有高度的认识,54%的参与者表示非常关注。
本研究纳入的 SCI 患者平均使用的常规药物数量与其他慢性疾病患者相同。尽管总体依从性较高,但与其他患者群体相比,参与者对其药物更为担忧。需要进一步研究以了解该人群的用药依从性和对药物的态度,特别是帮助慢性 SCI 患者对其药物治疗方案感到安全。