Guilcher Sara J T, Everall Amanda C, Patel Tejal, Packer Tanya L, Hitzig Sander L, Lofters Aisha K
Leslie Dan Faculty of Pharmacy, University of Toronto , Toronto , Canada.
Rehabilitation Sciences Institute, Faculty of Medicine, University of Toronto , Toronto , Canada.
J Spinal Cord Med. 2019 Oct;42(sup1):215-225. doi: 10.1080/10790268.2019.1637644.
People with spinal cord injury and dysfunction (SCI/D) often take multiple medications (. polypharmacy) to manage secondary health complications and multiple chronic conditions. Numerous healthcare providers are often involved in clinical care, increasing the risk of fragmented care, problematic polypharmacy, and conflicting health advice. These providers can play a crucial role in assisting patients with medication self-management to improve medication adherence. A qualitative study involving telephone interviews, following a semi-structured guide that explored healthcare providers' conceptualization of factors impacting medication adherence for persons with SCI/D. The interviews were transcribed and analyzed descriptively and interpretively using a constant comparative process with the assistance of data display matrices. Analysis was guided by an ecological model of medication adherence. Thirty-two healthcare providers from Canada, with varying clinical expertise. Not Applicable. Not Applicable. Providers identified several factors that impact medication adherence for persons with SCI/D, which were grouped into micro (medication and patient-related), meso- (provider-related) and macro- (health system-related) factors. Medication-related factors included side effects, effectiveness, safety, and regimen complexity. Patient-specific factors included medication knowledge, preferences/expectations/goals, severity and type of injury, cognitive function/mental health, time since injury, and caregiver support. Provider-related factors included knowledge/confidence and trust. Health system-related factors included access to healthcare and access to medications. While providers were able to identify several factors influencing medication adherence, micro-level factors were the most frequently discussed. Findings from this study indicate that strategies to optimize medication adherence for persons with SCI/D should be multi-faceted.
脊髓损伤和功能障碍(SCI/D)患者通常需要服用多种药物(即多重用药)来应对继发性健康并发症和多种慢性病。许多医疗服务提供者常常参与临床护理,这增加了护理碎片化、多重用药问题以及健康建议相互冲突的风险。这些提供者在协助患者进行药物自我管理以提高用药依从性方面可发挥关键作用。一项定性研究通过电话访谈展开,遵循半结构化指南,探讨医疗服务提供者对影响SCI/D患者用药依从性因素的概念化理解。访谈内容被转录,并借助数据展示矩阵,通过持续比较过程进行描述性和解释性分析。分析以用药依从性的生态模型为指导。来自加拿大的32名医疗服务提供者,具备不同的临床专业知识。不适用。不适用。提供者们确定了几个影响SCI/D患者用药依从性的因素,这些因素被分为微观(与药物和患者相关)、中观(与提供者相关)和宏观(与卫生系统相关)因素。与药物相关的因素包括副作用、疗效、安全性和治疗方案复杂性。患者特定因素包括用药知识、偏好/期望/目标、损伤的严重程度和类型、认知功能/心理健康、受伤时间以及护理人员的支持。与提供者相关的因素包括知识/信心和信任。与卫生系统相关的因素包括获得医疗服务和获取药物的机会。虽然提供者能够识别出几个影响用药依从性的因素,但微观层面的因素是讨论最为频繁的。本研究结果表明,优化SCI/D患者用药依从性的策略应是多方面的。