尘螨过敏的免疫疗法。
Immunotherapy of house dust mite allergy.
机构信息
a Department of Allergy , Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology , Wuhan , China.
出版信息
Hum Vaccin Immunother. 2017 Oct 3;13(10):2390-2396. doi: 10.1080/21645515.2017.1364823.
Abstract
House dust mite (HDM) is a predominant source of indoor aeroallergen worldwide, which induces allergic diseases including allergic rhinoconjunctivitis, allergic asthma, atopic eczema and other allergic skin diseases. Allergen specific immunotherapy (AIT) is the only potential disease-modifying treatment of HDM allergic subjects. However, AIT remains underused due to no universally accepted allergen standardization and a shortage of rigorous clinical studies to confirm safety and efficacy. With the effort of doctors and researchers in allergy field, efficacy, safety, standardization and strategy of AIT are being continuously developed. This review presents the updated research based on recently published trials and meta-analyses.
摘要
屋尘螨（HDM）是全球范围内主要的室内空气过敏原，可引起变应性疾病，包括变应性鼻炎、变应性哮喘、特应性皮炎和其他过敏性皮肤病。过敏原特异性免疫治疗（AIT）是治疗 HDM 过敏患者的唯一潜在的疾病修饰治疗方法。然而，由于没有普遍接受的过敏原标准化和缺乏严格的临床研究来确认安全性和有效性，AIT 的应用仍然不足。随着过敏领域医生和研究人员的努力，AIT 的疗效、安全性、标准化和策略正在不断发展。本综述根据最近发表的试验和荟萃分析提供了更新的研究。
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