Assemat Gaëtan, Dubocq Florian, Balayssac Stéphane, Lamoureux Catherine, Malet-Martino Myriam, Gilard Véronique
Groupe de RMN Biomédicale, Laboratoire SPCMIB (UMR CNRS 5068), Université Paul Sabatier, Université de Toulouse, 118 route de Narbonne, 31062 Toulouse Cedex, France.
SCL-Laboratoire d'Île-de-France, 1 rue Gabriel Vicaire, 75141 Paris Cedex 03, France.
Forensic Sci Int. 2017 Oct;279:88-95. doi: 10.1016/j.forsciint.2017.08.006. Epub 2017 Aug 12.
Forty one samples of herbal spices intended to be introduced into the European market and seized by the French customs were analysed with high-field H NMR. Nine synthetic cannabinoids (MAM-2201, JWH-073, JWH-210, JWH-122, JWH-081, JWH-250, UR-144, XLR-11 and AKB-48-5F) were detected and quantified. The ability of a compact benchtop low-field NMR spectrometer for a rapid screening of the content of herbal blends was then successfully explored for the first time. Even if low-field H NMR spectra are much less resolved than high-field spectra, we demonstrate that they provide valuable clues on the chemical structures of synthetic cannabinoids with the detection of some typical signals.
对41份拟引入欧洲市场并被法国海关查获的草本香料样本进行了高场¹H NMR分析。检测并定量了9种合成大麻素（MAM - 2201、JWH - 073、JWH - 210、JWH - 122、JWH - 081、JWH - 250、UR - 144、XLR - 11和AKB - 48 - 5F）。首次成功探索了紧凑型台式低场NMR光谱仪快速筛查草本混合物成分的能力。即使低场¹H NMR光谱的分辨率远低于高场光谱，但我们证明，通过检测一些典型信号，它们能为合成大麻素的化学结构提供有价值的线索。
