Srilekha Vennam, Krishna Gudikandula, Seshasrinivas Vutukuru, Charya Maringanti Alha Singara
Department of Biotechnology, Jawaharlal Nehru Technological University, Hyderabad 500085 (Telangana), India.
Department of Microbiology, Kakatiya University, Warangal-506009 (Telangana), India.
Res Pharm Sci. 2017 Aug;12(4):283-289. doi: 10.4103/1735-5362.212045.
The marine environment covers three quarters of the surface of the planet and is estimated to be home to more than 80% of life but yet it remains largely unexplored. It harbours a number of macro and microorganisms that have developed unique metabolic abilities to ensure their survival in diverse and hostile habitats, resulting in the biosynthesis of an array of secondary metabolites with specific activities. In this study, pigment forming bacterial strains were isolated from the sea surface inter tidal zones at different sampling sites along the Visakhapatnam coastal region. The bacterial isolates showed various types of colour pigments like pink, yellow, orange, and brown. Out of 26 pigmented isolates obtained, the bacterial isolate with bright yellow pigmentation was selected for further study. This strain was identified as by using morphological, physiological, biochemical and 16s rRNA sequencing methods. The pigment was extracted in methanol solvent and antibacterial activity of the pigments extracted from the bacteria was determined and it was found active against pathogenic bacteria. The pigment extract was tested for anti-inflammatory activity and was effective.
海洋环境覆盖了地球表面的四分之三,据估计地球上超过80%的生物都栖息于此,但它在很大程度上仍未被探索。海洋中存在许多大型和微生物,它们发展出了独特的代谢能力,以确保在多样且恶劣的栖息地中生存,从而生物合成了一系列具有特定活性的次生代谢产物。在本研究中,从维沙卡帕特南沿海地区不同采样点的海面潮间带分离出了形成色素的细菌菌株。这些细菌分离物呈现出各种颜色的色素,如粉色、黄色、橙色和棕色。在获得的26个有色分离物中,选择了具有亮黄色色素沉着的细菌分离物进行进一步研究。通过形态学、生理学、生物化学和16s rRNA测序方法,该菌株被鉴定为 。色素在甲醇溶剂中提取,并测定了从细菌中提取的色素的抗菌活性,发现其对病原菌具有活性。对色素提取物进行了抗炎活性测试,结果显示有效。