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改良根治性乳房切除术后瘢痕部位的皮肤红斑：复发性癌的意外表现

Cutaneous Erythema at Scar Site of Modified Radical Mastectomy: An Unexpected Manifestation of Recurrent Carcinoma.

作者信息

Nasralla Awrad Mohammed-Reda, Al-Duhileb Mohammed Abdulirazzaq, Arini Ali Jamal-Aldein, Amr Samir Sami

机构信息

Department of Surgery, King Fahad Specialist Hospital, Dammam, Saudi Arabia.

Department of Pathology and Laboratory Medicine, King Fahad Specialist Hospital, Dammam, Saudi Arabia.

出版信息

Case Rep Surg. 2017;2017:6879626. doi: 10.1155/2017/6879626. Epub 2017 Aug 10.

DOI:10.1155/2017/6879626
PMID:28856027
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5569635/
Abstract

A 44-year-old woman presented with marked erythema over right mastectomy scar, while on Herceptin therapy. She had neoadjuvant chemotherapy, modified radical mastectomy, and radiotherapy less than one year earlier for the treatment of invasive ductal carcinoma. On physical examination, no palpable masses were detected in the erythematous skin. A biopsy revealed permeation of the skin lymphatics by emboli of metastatic ductal carcinoma, similar to what is seen in inflammatory carcinoma. The involved skin was excised, followed by immediate reconstruction with transverse rectus abdominis muscle (TRAM) flap. On follow-up, the wound was healing well, with no signs of inflammation.

摘要

一名44岁女性在接受赫赛汀治疗时，右乳房切除疤痕处出现明显红斑。她在不到一年前接受了新辅助化疗、改良根治性乳房切除术和放疗，以治疗浸润性导管癌。体格检查发现，红斑皮肤处未触及肿块。活检显示转移性导管癌栓子浸润皮肤淋巴管，与炎性癌所见相似。切除受累皮肤，随后立即用腹直肌横形肌皮瓣（TRAM瓣）进行重建。随访时，伤口愈合良好，无炎症迹象。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee81/5569635/d969ce02e0ee/CRIS2017-6879626.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee81/5569635/cf48e68a2f9e/CRIS2017-6879626.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee81/5569635/4a5414803887/CRIS2017-6879626.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee81/5569635/d969ce02e0ee/CRIS2017-6879626.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee81/5569635/cf48e68a2f9e/CRIS2017-6879626.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee81/5569635/4a5414803887/CRIS2017-6879626.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee81/5569635/d969ce02e0ee/CRIS2017-6879626.003.jpg

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引用本文的文献

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Electrochemotherapy in the Treatment of Cutaneous Metastases from Breast Cancer: A Multicenter Cohort Analysis.电化学疗法治疗乳腺癌皮肤转移：一项多中心队列分析
Ann Surg Oncol. 2015 Dec;22 Suppl 3:S442-50. doi: 10.1245/s10434-015-4779-6. Epub 2015 Aug 5.
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Dermoscopic findings in cutaneous metastases.皮肤转移瘤的皮肤镜表现。
JAMA Dermatol. 2014 Apr;150(4):429-33. doi: 10.1001/jamadermatol.2013.8502.
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Postmastectomy-postirradiation atypical vascular lesion of the skin: report of 2 cases.乳房切除术后放疗后皮肤非典型血管病变：2例报告
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Vascular proliferations of the skin after radiation therapy for breast cancer: clinicopathologic analysis of a series in favor of a benign process: a study from the French Sarcoma Group.乳腺癌放疗后皮肤血管增生：支持良性过程的系列病例临床病理分析：来自法国肉瘤研究组的一项研究
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Locoregional recurrence after mastectomy: incidence and outcomes.乳房切除术后局部区域复发：发生率及结局
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