Hosseinpour Reza, Yavari Barhaghtalab Mohammad Javad
Cancer institute, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Department of General Surgery, Shahid Beheshti Hospital, Yasuj University of Medical Sciences, Yasuj, Iran.
Case Rep Dermatol Med. 2021 Feb 16;2021:6673289. doi: 10.1155/2021/6673289. eCollection 2021.
Five to ten percent of the patients with operable breast cancer develop a chest wall recurrence within 10 years following the mastectomy. One of the most distressing presentations of locally recurrent breast cancer is the appearance of cutaneous metastases. To the best of authors' knowledge, there is no study distinguishing skin metastasis from local recurrence, so the main aim of this report was to elucidate if these two features are important in the prognosis and management of the disease. . A 51-year-old woman referred to the breast clinic due to a painful mass in the left breast. The patient underwent the modified radical mastectomy (MRM) and left axillary lymph node dissection followed by 30 sessions of radiotherapy and 8 sessions of chemotherapy (T3N1M0, ER-, and HER2+). About 15 months after the surgery, she presented with redness and eruptive lesions over the mastectomy scar that increased in size within a three-month follow-up.
Mastectomy is not an absolute cure in the treatment of an invasive breast cancer because almost always, there is a recurrence risk and possibility of metastasis. It is vital to differentiate between local recurrence and skin metastasis because it would alter the overall treatment decision, prognosis, and patient outcomes.
5%至10%的可手术乳腺癌患者在乳房切除术后10年内会出现胸壁复发。局部复发性乳腺癌最令人苦恼的表现之一是皮肤转移的出现。据作者所知，尚无研究区分皮肤转移与局部复发，因此本报告的主要目的是阐明这两个特征在该疾病的预后和管理中是否重要。一名51岁女性因左乳疼痛性肿块转诊至乳腺科。患者接受了改良根治性乳房切除术（MRM）和左腋窝淋巴结清扫术，随后进行了30次放疗和8次化疗（T3N1M0，雌激素受体阴性，人表皮生长因子受体2阳性）。术后约15个月，她在乳房切除术后的瘢痕处出现发红和皮疹样病变，在三个月的随访中病变增大。
乳房切除术并非浸润性乳腺癌治疗的绝对治愈方法，因为几乎总是存在复发风险和转移可能性。区分局部复发和皮肤转移至关重要，因为这会改变整体治疗决策、预后和患者结局。
