Department of Psychology and Institute for Neuroscience, Texas A&M University, College Station, TX, USA.
Neuron. 2017 Aug 30;95(5):988-990. doi: 10.1016/j.neuron.2017.08.020.
Input specificity is a fundamental property of long-term potentiation (LTP), but it is not known if learning is mediated by synapse-specific plasticity. Kim and Cho (2017) now show that fear conditioning is mediated by synapse-specific LTP in the amygdala, allowing animals to discriminate stimuli that predict threat from those that do not.
输入特异性是长时程增强(LTP)的一个基本特性,但学习是否由突触特异性可塑性介导尚不清楚。Kim 和 Cho(2017)现在表明,恐惧条件反射是由杏仁核中的突触特异性 LTP 介导的,使动物能够区分预测威胁的刺激与不预测威胁的刺激。