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微创冠状动脉旁路移植术的国际概况与进展

Less-invasive coronary artery bypass grafting international landscape and progress.

作者信息

Kikuchi Keita, Mori Makoto

机构信息

aDepartment of Cardiac Surgery, Wuhan Asia Heart Hospital, Wuhan, China bSection of Cardiac Surgery, Yale School of Medicine, Connecticut, USA.

出版信息

Curr Opin Cardiol. 2017 Nov;32(6):715-721. doi: 10.1097/HCO.0000000000000461.

Abstract

PURPOSE OF REVIEW

Less-invasive coronary artery bypass grafting (CABG) has evolved in multiple forms. Specifically noteworthy are recent technical refinement and reports of mid-term outcomes from well designed trials and observational studies in off-pump CABG, minimally invasive coronary artery bypass grafting (MICS CABG) and hybrid coronary revascularization (HCR). This review summarizes the historical evolution and recent development in less-invasive coronary artery bypass grafting.

RECENT FINDINGS

A recent network meta-analysis of CABG with various degree of aortic manipulation demonstrated that no-touch technique may result in a significant reduction of postoperative stroke risk. A 5-year follow-up data of CORONARY study demonstrated that there was no significant difference in the rate of mortality, repeat revascularization, or primary composite outcome. The first multicenter observational study of HCR and PCI cohorts demonstrated that there was no significant difference in major adverse cardiac and cerebrovascular events at 12 months, with diverging event-free survival favoring HCR toward the end of the study period.

SUMMARY

Less-invasive CABG continues to evolve in multiple forms. MICS CABG with the use of bilateral internal thoracic arteries preserves the sternum while allowing for a robust revascularization. HCR augments each form of less-invasive CABG, and is expected to play a larger role in the near future.

摘要

综述目的

微创冠状动脉旁路移植术(CABG)已演变成多种形式。特别值得注意的是近期的技术改进以及来自非体外循环CABG、微创冠状动脉旁路移植术(MICS CABG)和杂交冠状动脉血运重建术(HCR)的精心设计试验和观察性研究的中期结果报告。本综述总结了微创冠状动脉旁路移植术的历史演变和近期发展。

近期发现

最近一项对不同程度主动脉操作的CABG进行的网络荟萃分析表明,非接触技术可能会显著降低术后中风风险。CORONARY研究的5年随访数据表明,死亡率、再次血运重建率或主要复合结局方面无显著差异。第一项关于HCR和PCI队列的多中心观察性研究表明,12个月时主要不良心脑血管事件无显著差异,在研究期结束时,无事件生存率有利于HCR。

总结

微创CABG继续以多种形式发展。使用双侧胸廓内动脉的MICS CABG保留了胸骨,同时实现了强有力的血运重建。HCR增强了每种微创CABG形式,预计在不久的将来将发挥更大作用。

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