Institute for Health Services Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Institute for Health Services Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
J Invest Dermatol. 2017 Oct;137(10):2069-2077. doi: 10.1016/j.jid.2017.05.020. Epub 2017 Aug 30.
This review aims to systematically evaluate studies on the measurement properties of patient-reported outcome measures in pruritus, especially for use in clinical trials. Validation studies on instruments were identified based on a PubMed literature search. The consensus-based standards for the selection of health status measurement instruments checklist was used to evaluate the studies' methodological quality, and the consensus-based standards for the selection of health status measurement instruments criteria were used to synthesize the instruments' measurement properties. Twenty-three studies were included, which contain 37 examinations of reliability and/or validity for 23 different outcome measures. The methodological quality of reliability and validity evidence was moderate for six outcome measures; for these measures, psychometric property rating was adequate too, making them suitable for use in clinical trials. Itch severity scale, itchy quality of life, numerical rating scale-6, numerical rating scale-11, visual analog scale (horizontal), and verbal numerical rating scale-4 are currently the most appropriate patient-reported outcome measures with regard to overall reliability and validity.
本综述旨在系统评估瘙痒患者报告结局测量工具的测量特性研究，尤其是在临床试验中的应用。根据 PubMed 文献检索确定了仪器的验证研究。采用共识基础的健康状况测量仪器选择标准检查表来评估研究的方法学质量，并采用共识基础的健康状况测量仪器选择标准来综合仪器的测量特性。共纳入 23 项研究，其中包含 23 种不同结局测量工具的 37 项可靠性和/或有效性检验。6 种结局测量工具的可靠性和有效性证据的方法学质量为中等；对于这些措施，心理测量特性评级也是足够的，因此它们适合在临床试验中使用。瘙痒严重程度量表、瘙痒生活质量量表、数字评定量表-6、数字评定量表-11、视觉模拟量表（水平）和口头数字评定量表-4 是目前在整体可靠性和有效性方面最适合的患者报告结局测量工具。
