Kunkel Thaddeus, Wang Hongbing
Neuroscience Program, Michigan State University, East Lansing, MI 48824, United States.
Neuroscience Program, Michigan State University, East Lansing, MI 48824, United States; Department of Physiology, Michigan State University, East Lansing, MI 48824, United States.
Behav Brain Res. 2018 Jan 15;336:173-176. doi: 10.1016/j.bbr.2017.08.038. Epub 2017 Aug 30.
A series of behavioral tests measuring social dominance, social motivation, and non-social motivation are examined in adult male C57BL6 mice. By using the well-known tube dominance test to determine social dominance and rank, we find that, in the absence of competition for resource and mating, group-housed mouse cage-mates display stable and mostly linear and transitive social hierarchies. Mice with top and bottom social ranks are subjected to a three-chamber social interaction test to measure social motivation. The top ranked mice spend more time interacting with a stranger mouse than the bottom ranked mice, suggesting that social dominance may positively influence social motivation. When subjected to a novel environment, mice with different social ranks show similar locomotion and exploring activity in the open field test, suggesting no detectable difference in certain aspects of non-social motivation. These results demonstrate a behavioral correlation between social dominance and social motivation.
在成年雄性C57BL6小鼠中进行了一系列测量社会支配地位、社会动机和非社会动机的行为测试。通过使用著名的管子支配测试来确定社会支配地位和等级，我们发现，在没有资源和交配竞争的情况下，群居小鼠笼内同伴表现出稳定且大多呈线性和可传递的社会等级制度。将具有最高和最低社会等级的小鼠进行三室社会互动测试以测量社会动机。社会等级最高的小鼠比等级最低的小鼠花费更多时间与陌生小鼠互动，这表明社会支配地位可能对社会动机产生积极影响。在新环境中，不同社会等级的小鼠在旷场试验中表现出相似的运动和探索活动，这表明在非社会动机的某些方面没有可检测到的差异。这些结果证明了社会支配地位与社会动机之间的行为相关性。
