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圆柱细胞乳头状瘤(嗜酸性细胞性鼻内翻性乳头状瘤):5例临床病理研究

Cylindrical Cell Papilloma (Oncocytic Schneiderian Papilloma): Clinicopathological Study of Five Cases.

作者信息

Darwish Abdulla, Al-Abdulla Amal

机构信息

Pathology Department, Bahrain Defence Force Medical Services Kingdom of Bahrain.

Pathology and ENT Departments, Bahrain Defence Force Medical Services Kingdom of Bahrain.

出版信息

Oman Med J. 2012 Sep;27(5):e039. doi: 10.5001/omj.2012.106.

Abstract

OBJECTIVE

To study the clinicopathological findings of cylindrical cell papilloma (oncocytic schneiderian papilloma) diagnosed among patients at Bahrain Defense Force Hospital with review of literature.

METHODS

All cases of cylindrical cell papilloma were retrieved from the pathology register from 2006-2010. The medical records of the cases were studied for age, sex, clinical presentation, and imaging reports along with the histopathological findings.

RESULTS

Five cases were found and showed male to female ratio 4:1. Their ages were between 36-71 years with average age of 55 years. The main symptom found was unilateral nasal obstruction mainly involving the left side. All papillomas were removed by endoscopic sinus surgery. Four patients had regular followup with complete recovery, while only one case was lost for followup.

CONCLUSION

Cylindrical cell papilloma is a variant of sinonasal schneiderian papilloma. Although most are benign complete excision is the treatment of choice to prevent tumour recurrence as a proportion exhibit unpredictable biological behavior. This study is an important reminder for both clinicians and pathologists to recognize this tumor and to differentiate it from other tumours and rhinosporidiosis. Regular followup is an important strategy for complete recovery and tumour-free surveillance.

摘要

目的

研究巴林国防军医院确诊的柱状细胞乳头状瘤(嗜酸性粒细胞性施耐德乳头状瘤)的临床病理特征,并复习相关文献。

方法

从2006年至2010年的病理登记册中检索所有柱状细胞乳头状瘤病例。研究这些病例的病历,包括年龄、性别、临床表现、影像学报告以及组织病理学检查结果。

结果

共发现5例,男女比例为4:1。年龄在36至71岁之间,平均年龄为55岁。主要症状为单侧鼻塞,主要累及左侧。所有乳头状瘤均通过鼻内镜鼻窦手术切除。4例患者定期随访,完全康复,仅1例失访。

结论

柱状细胞乳头状瘤是鼻窦施耐德乳头状瘤的一种变体。尽管大多数为良性,但为防止肿瘤复发,完整切除是首选治疗方法,因为部分病例表现出不可预测的生物学行为。本研究对临床医生和病理学家而言是一个重要提示,提醒他们认识这种肿瘤,并将其与其他肿瘤及鼻孢子虫病相鉴别。定期随访是实现完全康复和无瘤监测的重要策略。

相似文献

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[Oncocytic schneiderian papilloma. A case report].
An Otorrinolaringol Ibero Am. 2005;32(2):115-23.

本文引用的文献

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Inverted papilloma of the middle ear: a case report and review of the literature.中耳内翻性乳头状瘤:一例报告并文献复习
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Primary temporal inverted papilloma with premalignant change.伴有癌前病变的原发性颞部内翻性乳头状瘤
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Head neck pathol radiology pathology classics.头颈病理学与放射学经典著作。
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