Choudhary Anil Kumar, Jha Nawal K
Ram Manohar Lohia Hospital, New Delhi, India;
Rajendra Institute of Medical Sciences, Ranchi, India.
Can Urol Assoc J. 2015 Jan-Feb;9(1-2):E22-6. doi: 10.5489/cuaj.2291.
We analyzed the outcomes of augmented buccal mucosa graft (BMG) dorsal onlay urethroplasty and anastomotic urethroplasty in the management of urethral stricture.
Patients having a stricture length more than 2 cm were treated by augmented BMG dorsal onlay urethroplasty; patients with a stricture length less than 2 cm were managed by excision and end-to-end anastomotic urethroplasty. The postoperative retrograde urethrogram, micturating cystourethrogram, and uroflowmetry were compared to preoperative values. The postoperative subjective symptoms and complications were recorded and analyzed.
In total, 90 patients were included in this study. Forty-five patients had an average stricture length of 5.9 cm; they underwent BMG augmented dorsal onlay urethroplasty. Of these, 7 (15.55%) patients came with recurrence, while 38 (84.44%) were asymptomatic, in the average follow-up period of 32.8 months. The next 45 patients underwent excision of the stricture and end-to-end anastomosis. Of these, 6 (13.33%) failed on therapy and the remaining 39 (86.66%) were asymptomatic during the average follow-up period of 28.4 months.
The technique of BMG dorsal onlay is easy to do, it is very reliable, has high success rate, less postoperative complications and better patient satisfaction compared to anastomotic urethroplasty. Our study has its limitations. Recurrent cases of urethroplasty and hypospadias were excluded from this study. Recurrent stricture cases were eliminated to overcome bias. Cases of hypospadias are still best treated by axial or random penile skin flap as BMG augmentation cannot create a long urethral tube. Based on our 4-year experience, we recommend BMG augmented urethroplasty long and short segment stricture of the urethra.
我们分析了在尿道狭窄治疗中,口腔黏膜补片(BMG)背侧镶嵌尿道成形术和吻合性尿道成形术的疗效。
狭窄长度超过2cm的患者采用BMG背侧镶嵌尿道成形术治疗;狭窄长度小于2cm的患者采用切除及端端吻合性尿道成形术治疗。将术后逆行尿道造影、排尿性膀胱尿道造影及尿流率测定结果与术前值进行比较。记录并分析术后主观症状及并发症。
本研究共纳入90例患者。45例患者平均狭窄长度为5.9cm;他们接受了BMG增强背侧镶嵌尿道成形术。其中,7例(15.55%)患者复发,而在平均32.8个月的随访期内,38例(84.44%)患者无症状。另外45例患者接受了狭窄切除及端端吻合术。其中,6例(13.33%)治疗失败,在平均28.4个月的随访期内,其余39例(86.66%)患者无症状。
与吻合性尿道成形术相比,BMG背侧镶嵌技术操作简便、可靠性高、成功率高、术后并发症少且患者满意度更高。我们的研究存在局限性。本研究排除了尿道成形术复发病例及尿道下裂病例。为克服偏倚,排除了复发性狭窄病例。尿道下裂病例仍最好采用轴型或随意阴茎皮瓣治疗,因为BMG增强术无法构建长尿道管。基于我们4年的经验,我们推荐BMG增强尿道成形术用于尿道长短节段狭窄。