Bari Samiha, Metgud Rashmi, Vyas Zankhana, Tak Aniruddh
Department of Oral and Maxillofacial Pathology, Pacific Dental College and Hospital, Udaipur, Rajasthan, India.
J Cancer Res Ther. 2017 Jul-Sep;13(3):399-405. doi: 10.4103/0973-1482.179524.
Worldwide estimates of oral submucous fibrosis (OSMF) show a confinement to Indians and Southeast Asians. In India, the prevalence of OSMF has increased over the past four decades from 0.03% to 6.42%. The condition is well recognized for its malignant potential rate of 7-30%. The condition has a multifactorial etiology and may remain either stationary or become severe, leaving an individual physically challenged both physically and psychologically. Hence, the study aims at reviewing studies done on various etiological factors leading to its onset. Their analysis may serve as an adjunct in defining the broad spectrum of the causation of this potentially malignant disorder.
全球范围内对口腔黏膜下纤维化（OSMF）的估计表明，该病主要局限于印度人和东南亚人。在印度，过去四十年来OSMF的患病率从0.03%上升至6.42%。该疾病因其7%-30%的恶变率而广为人知。其病因是多因素的，病情可能保持稳定或加重，给患者带来身体和心理上的双重挑战。因此，本研究旨在回顾关于导致其发病的各种病因的研究。对这些研究的分析可能有助于明确这种潜在恶性疾病的广泛病因。
