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在存在髋关节假体的情况下评估商业治疗计划系统各种剂量计算算法的准确性,并与蒙特卡罗方法进行比较。

Evaluation of the accuracy of various dose calculation algorithms of a commercial treatment planning system in the presence of hip prosthesis and comparison with Monte Carlo.

作者信息

Mohammadi Kheirollah, Hassani Mohsen, Ghorbani Mahdi, Farhood Bagher, Knaup Courtney

机构信息

Department of Physics, Malek-Ashtar University of Technology, Tehran, Iran.

Department of Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran.

出版信息

J Cancer Res Ther. 2017 Jul-Sep;13(3):501-509. doi: 10.4103/0973-1482.204903.

Abstract

PURPOSE

High atomic number elements are commonly used in a hip prosthesis which can cause uncertainty in accurate dose calculations in radiation therapy. The aim of this study is to assess the accuracy of the three various algorithms of ISOgray treatment planning system in the presence of hip prosthesis by Monte Carlo (MC).

MATERIALS AND METHODS

A MC model of Siemens PRIMUS linear accelerator has been built and verified by the measured data of the different algorithms of ISOgray treatment planning systems (TPS) in 6 and 15 MV photon beam energies. Two types of hip prosthesis have been used: stainless steel and titanium. The accuracy of mentioned dose calculation algorithms in the presence of hip prosthesis was evaluated.

RESULTS

There were 24.78%, 27.68%, and 27.72% errors in fast Fourier transform (FFT) Convolution, collapsed cone (CC), and superposition in 6 MV photon beam and 26.45%, 30.45%, and 28.63% in 15 MV photon beam for titanium type, respectively. However, there were 32.84%, 35.89%, and 35.57% in 6 MV photon beam and 38.81%, 47.31%, and 39.91% errors in 15 MV photon beam in steel type, respectively. In addition, the ISOgray TPS algorithms are not able to predict the dose enhancement and reduction at the proximal and distal prosthesis interfaces, respectively.

CONCLUSIONS

Hip prosthesis creates a considerable disturbance in dose distribution which cannot be predicted accurately by the FFT convolution, CC, and superposition algorithms. It is recommended to use of MC-based TPS for the treatment fields including the hip prosthesis.

摘要

目的

高原子序数元素常用于髋关节假体,这可能会在放射治疗的精确剂量计算中导致不确定性。本研究的目的是通过蒙特卡罗(MC)方法评估在存在髋关节假体的情况下ISOgray治疗计划系统的三种不同算法的准确性。

材料与方法

建立了西门子PRIMUS直线加速器的MC模型,并通过ISOgray治疗计划系统(TPS)在6和15MV光子束能量下不同算法的测量数据进行了验证。使用了两种类型的髋关节假体:不锈钢和钛。评估了在存在髋关节假体的情况下上述剂量计算算法的准确性。

结果

对于钛型假体,在6MV光子束中,快速傅里叶变换(FFT)卷积、坍缩圆锥(CC)和叠加算法的误差分别为24.78%、27.68%和27.72%,在15MV光子束中分别为26.45%、30.45%和28.63%。然而,对于钢型假体,在6MV光子束中的误差分别为32.84%、35.89%和35.57%,在15MV光子束中的误差分别为38.81%、47.31%和39.91%。此外,ISOgray TPS算法无法分别预测假体近端和远端界面处的剂量增强和降低。

结论

髋关节假体在剂量分布中产生了相当大的干扰,FFT卷积、CC和叠加算法无法准确预测。建议对包括髋关节假体的治疗野使用基于MC的TPS。

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