Mesbahi Asghar, Nejad Farshad Seyed
Medical Physics Department, Medical School, Tabriz University of Medical Sciences, Tabriz, Iran.
Radiat Med. 2007 Dec;25(10):529-35. doi: 10.1007/s11604-007-0181-z. Epub 2007 Dec 25.
The purpose of this study was to investigate the dosimetric effect of various hip prostheses on pelvis lateral fields treated by a 9-MV photon beam using Monte Carlo (MC) and effective path-length (EPL) methods.
The head of the Neptun 10 pc linac was simulated using the MCNP4C MC code. The accuracy of the MC model was evaluated using measured dosimetric features including depth dose values and dose profiles in a water phantom. The Alfard treatment planning system (TPS) was used for EPL calculations. A virtual water phantom with dimensions of 30 x 30 x 30 cm(3) and a cube with dimensions of 4 x 4 x 4 cm(3) made of various metals centered in 12 cm depth was used for MC and EPL calculations. Various materials including titanium, Co-Cr-Mo, and steel alloys were used as hip prostheses.
Our results showed significant attenuation in absorbed dose for points after and inside the prostheses. Attenuations of 32%, 54% and 55% were seen for titanium, Co-Cr-Mo, and steel alloys, respectively, at a distance of 5 cm from the prosthesis. Considerable dose increase (up to 18%) was found at the water-prosthesis interface due to back-scattered electrons using the MC method. The results of EPL calculations for the titanium implant were comparable to the MC calculations. This method, however, was not able to predict the interface effect or calculate accurately the absorbed dose in the presence of the Co-Cr-Mo and steel prostheses.
The dose perturbation effect of hip prostheses is significant and cannot be predicted accurately by the EPL method for Co-Cr-Mo or steel prostheses. The use of MC-based TPS is recommended for treatments requiring fields passing through hip prostheses.
本研究旨在使用蒙特卡罗(MC)方法和有效路径长度(EPL)方法,研究各种髋关节假体对9兆伏光子束治疗骨盆侧野的剂量学影响。
使用MCNP4C MC代码模拟Neptun 10 pc直线加速器的机头。使用测量的剂量学特征(包括水模中的深度剂量值和剂量分布)评估MC模型的准确性。使用Alfard治疗计划系统(TPS)进行EPL计算。将尺寸为30×30×30 cm³的虚拟水模和由各种金属制成、尺寸为4×4×4 cm³且位于12 cm深度中心的立方体用于MC和EPL计算。各种材料(包括钛、钴铬钼合金和钢合金)用作髋关节假体。
我们的结果显示假体后方和内部各点的吸收剂量有显著衰减。在距假体5 cm处,钛、钴铬钼合金和钢合金的衰减分别为32%、54%和55%。使用MC方法时,由于背散射电子,在水-假体界面处发现剂量显著增加(高达18%)。钛植入物的EPL计算结果与MC计算结果相当。然而,该方法无法预测界面效应,也无法在存在钴铬钼合金和钢假体的情况下准确计算吸收剂量。
髋关节假体的剂量扰动效应显著,对于钴铬钼合金或钢假体,EPL方法无法准确预测。对于需要野穿过髋关节假体的治疗,建议使用基于MC的TPS。