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狭盐性淡水硬骨鱼:银鲫(Carassius auratus gibelio Bloch)中肾磷酸盐分泌的刺激作用

Stimulation of renal phosphate secretion in the stenohaline freshwater teleost: Carassius auratus gibelio Bloch.

作者信息

Kaune R, Hentschel H

出版信息

Comp Biochem Physiol A Comp Physiol. 1987;87(2):359-62. doi: 10.1016/0300-9629(87)90136-8.

DOI:10.1016/0300-9629(87)90136-8
PMID:2886277
Abstract
  1. Renal excretion of phosphate in the Prussian carp was modulated by tubular reabsorption and tubular secretion. 2. Under the conditions of an i.v. phosphate-load during which the plasma concentration of phosphate was doubled, 65% of the phosphate load was excreted by the kidney, mainly by tubular secretion. 3. The renal clearance of PAH markedly exceeded the clearance of polyfructosan which could be used for the measurement of the GFR. 4. A transport maximum for tubular PAH secretion was reached at plasma concentrations of about 250 mumol/l.
摘要
  1. 鲤鱼肾脏对磷酸盐的排泄通过肾小管重吸收和肾小管分泌进行调节。2. 在静脉注射磷酸盐负荷的情况下,血浆磷酸盐浓度加倍,65%的磷酸盐负荷由肾脏排泄,主要通过肾小管分泌。3. 对氨基马尿酸(PAH)的肾清除率明显超过可用于测量肾小球滤过率(GFR)的多聚果糖清除率。4. 当血浆浓度约为250μmol/L时,肾小管对PAH的分泌达到转运最大值。

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