Martin Julie Langan, McLean Gary, Martin Daniel, Cantwell Roch, Smith Daniel J
Institute of Health and Wellbeing, College of Medical, Veterinary and Life Sciences, University of Glasgow, Mental Health and Wellbeing, Gartnavel Royal Hospital, Glasgow, UK.
Perinatal Mental Health Service and West of Scotland Mother and Baby Unit, Leverndale Hospital, Glasgow, UK.
BMJ Open. 2017 Sep 1;7(9):e016908. doi: 10.1136/bmjopen-2017-016908.
To identify factors associated with: admission to a specialist mother and baby unit (MBU) and the impact of perinatal mental illness on early childhood development using a data linkage approach in the 2 years prechildbirth and postchildbirth.
Scottish maternity records (SMR02) were linked to psychiatric hospital admissions (SMR04). 3290 pregnancy-related psychiatric admissions for 1730 women were assessed. To investigate factors associated with MBU admission, the group of mothers admitted to an MBU were compared with those admitted to general psychiatric wards. To assess the impact of perinatal mental illness on early child development, a pragmatic indicator for 'at potential risk of adversity', defined as a child who was recorded as requiring intensive treatment at any time under the health plan indicators (HPI) and/or who had no record of completing three doses of the 5-in-1 vaccine by 12 months was generated. Logistic regression models were used to describe the association between each variable and the risk of admission between those with a history of prior psychiatric admission and those without.
Women admitted to an MBU were significantly more likely to be admitted with non-affective psychosis (OR=1.97, 95% CI 1.22 to 3.18), affective psychosis (OR=2.44, 95% CI 1.37 to 4.33) and non-psychotic depressive episodes (OR=1.93, 95% CI 1.42 to 2.63). They were less likely to come from deprived areas (OR=0.68 95% CI 0.49 to 0.93). Women with a previous history of psychiatric admission were significantly more likely to be located in the two most deprived quintiles. Almost one-third (29%) of children born to mothers with a pregnancy-related psychiatric admission were assessed as 'at potential risk of adversity.'
A health informatics approach has potential for improving understanding of social and clinical factors, which contribute to the outcomes of perinatal mental illness, as well as potential adverse developmental outcomes for offspring.
通过在分娩前和分娩后的2年中采用数据链接方法,确定与以下因素相关的因素:入住母婴专科病房(MBU)以及围产期精神疾病对幼儿发育的影响。
将苏格兰产妇记录(SMR02)与精神病医院入院记录(SMR04)相链接。对1730名女性的3290例与妊娠相关的精神病入院病例进行了评估。为了调查与入住MBU相关的因素,将入住MBU的母亲组与入住普通精神科病房的母亲组进行比较。为了评估围产期精神疾病对儿童早期发育的影响,生成了一个“处于潜在逆境风险”的实用指标,定义为在健康计划指标(HPI)下被记录为随时需要强化治疗的儿童和/或在12个月时没有完成三剂五联疫苗接种记录的儿童。使用逻辑回归模型描述每个变量与有精神病入院史者和无精神病入院史者之间的入院风险之间的关联。
入住MBU的女性因非情感性精神病入院的可能性显著更高(OR = 1.97,95%CI 1.22至3.18)、情感性精神病(OR = 2.44,95%CI 1.37至4.33)和非精神病性抑郁发作(OR = 1.93,95%CI 1.42至2.63)。她们来自贫困地区的可能性较小(OR = 0.68,95%CI 0.49至0.93)。有精神病入院史的女性更有可能处于最贫困的两个五分位数。有与妊娠相关的精神病入院史的母亲所生的孩子中,近三分之一(29%)被评估为“处于潜在逆境风险”。
健康信息学方法有可能增进对社会和临床因素的理解,这些因素有助于围产期精神疾病的结局以及后代潜在的不良发育结局。