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不同临床环境中持续气道正压通气(CPAP)依从性的预测因素:初级保健与睡眠单元对比

Predictors of CPAP compliance in different clinical settings: primary care versus sleep unit.

作者信息

Nadal Núria, de Batlle Jordi, Barbé Ferran, Marsal Josep Ramon, Sánchez-de-la-Torre Alicia, Tarraubella Nuria, Lavega Merce, Sánchez-de-la-Torre Manuel

机构信息

Hospital Universitari Arnau de Vilanova and Santa Maria. IRBLleida, Lleida, Spain.

Primary Care Unit of Lleida, Catalonia, Spain.

出版信息

Sleep Breath. 2018 Mar;22(1):157-163. doi: 10.1007/s11325-017-1549-7. Epub 2017 Sep 1.

Abstract

BACKGROUND

Good adherence to continuous positive airway pressure (CPAP) treatment improves the patient's quality of life and decreases the risk of cardiovascular disease. Previous studies that have analyzed the adherence to CPAP were performed in a sleep unit (SU) setting. The involvement of primary care (PC) in the management of obstructive sleep apnea (OSA) patients receiving CPAP treatment could introduce factors related to the adherence to treatment.

OBJECTIVES

The objective was to compare the baseline predictors of CPAP compliance in SU and PC settings.

METHODS

OSA patients treated with CPAP were followed for 6 months in SU or PC setting. We included baseline clinical and anthropometrical variables, the Epworth Sleep Scale (ESS) score, the quality of life index, and the Charlson index. A logistic regression was performed for each group to determine the CPAP compliance predictors. Discrimination and calibration were performed using the area under the curve and Hosmer-Lemeshow tests.

RESULTS

We included 191 patients: 91 in the PC group and 100 in the SU group. In 74.9% of the patients, the compliance was ≥ 4 h per day, with 80% compliance in the SU setting and 69.2% compliance in the PC setting (p = 0.087). The predictors of CPAP compliance were different between SU and PC settings. Body mass index, ESS, and CPAP pressure were predictors in the SU setting, and ESS, gender, and waist circumference were predictors in the PC setting.

CONCLUSIONS

The predictors of adequate CPAP compliance vary between SU and PC settings. Detecting compliance predictors could help in the planning of early interventions to improve CPAP adherence.

摘要

背景

良好地坚持持续气道正压通气(CPAP)治疗可改善患者生活质量并降低心血管疾病风险。以往分析CPAP依从性的研究是在睡眠单元(SU)环境中进行的。初级保健(PC)参与接受CPAP治疗的阻塞性睡眠呼吸暂停(OSA)患者的管理可能会引入与治疗依从性相关的因素。

目的

目的是比较在SU和PC环境中CPAP依从性的基线预测因素。

方法

接受CPAP治疗的OSA患者在SU或PC环境中随访6个月。我们纳入了基线临床和人体测量学变量、爱泼华嗜睡量表(ESS)评分、生活质量指数和查尔森指数。对每组进行逻辑回归以确定CPAP依从性预测因素。使用曲线下面积和霍斯默-莱梅肖检验进行区分和校准。

结果

我们纳入了191例患者:PC组91例,SU组100例。74.9%的患者依从性≥每天4小时,SU环境中的依从性为80%,PC环境中的依从性为69.2%(p = 0.087)。SU和PC环境中CPAP依从性的预测因素不同。体重指数、ESS和CPAP压力是SU环境中的预测因素,而ESS、性别和腰围是PC环境中的预测因素。

结论

SU和PC环境中足够的CPAP依从性预测因素有所不同。检测依从性预测因素有助于规划早期干预措施以提高CPAP依从性。

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