Siddiqi Hasan K, Bossone Eduardo, Pyeritz Reed E, Eagle Kim A
Cardiovascular Medicine, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
"Cava de' Tirreni" Cardiology Unit, Heart Department, Scuola Medica Salernitana, University Hospital, Via Pr. Amedeo, 36, Lauro (AV), Salerno 83023, Italy.
Heart Fail Clin. 2017 Oct;13(4):697-701. doi: 10.1016/j.hfc.2017.05.006. Epub 2017 Jul 11.
Acute aortic syndromes are highly morbid conditions that require prompt diagnosis and management. Aortic dissections have rhythmic patterns, with notable peaks at certain points in every 24 hours as well as weekly and seasonal variations. Several retrospective studies have assessed the chronobiology of acute aortic dissections and there seems to be a winter seasonal peak and morning daily peak in incidence. Although the pathophysiology of this chronobiology is unclear, there are several environmental and physiologic possibilities. This article reviews the major studies examining the chronobiology of acute aortic dissection, and summarizes some theories on the pathophysiology of this phenomenon.
